Results 71 to 80 of about 6,990 (193)

Computer‐Assisted Sperm Analysis (CASA) Versus Manual Evaluation and the Clinical Significance of Sperm Hyperactivated Motility

Andrology, Volume 14, Issue 5, Page 1401-1412, July 2026.
ABSTRACT Background Semen analysis remains the first‐line diagnostic test for male infertility, although it is affected by operator subjectivity. Computer‐assisted sperm analysis (CASA) is proposed to improve objectivity; however, its accuracy and clinical relevance remain uncertain.
Maria Emanuela Ragosta, Giulia Traini, Francesca Benini, Margherita Montereggi, Federica Bini, Lara Tamburrino, Linda Vignozzi, Elisabetta Baldi, Sara Marchiani   +8 more
wiley   +1 more source

Microscale Surface Tension and its Applications

Micromachines, 2019
More than 200 years since the earliest scientific investigations by Young, Laplace and Plateau, liquid surface tension is still the object of thriving fundamental and applied research [...]
Pierre Lambert, Massimo Mastrangeli
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Modeling and Evaluation of Penetration Process Based on 3D Mechanical Simulation

Sensors
In biological micromanipulation, cell penetration is a typical procedure that precedes cell injection or oocyte enucleation. During this procedure, cells usually undergo significant deformation, which leads to cell damage.
Xiaohan Chen, Huiying Gong, Bin Yang, Zengshuo Wang, Yaowei Liu, Lu Zhou, Xin Zhao, Mingzhu Sun   +7 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, Volume 16, Issue 6, Page 1102-1114, June 2026.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Nanodiamond Quantum Sensors for Probing Free Radical Biology

Advanced Functional Materials, Volume 36, Issue 45, 5 June 2026.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source

RENAL‐CHIP: Rejection Evaluation via Non‐Invasive Analysis of Circulating Podocytes With Herringbone‐Chip Isolation Platform

Advanced Science, Volume 13, Issue 31, 4 June 2026.
RENAL‐CHIP converts 1 mL of peripheral blood into a biopsy‐equivalent readout of renal‐allograft fate. By magnetic capture and release of donor‐derived circulating podocytes through a herringbone microfluidic chip, 84% capture, 96% release and single‐cell RNA evidence of rejection‐specific immunity are achieved.
Juan Song, Yilong Liu, Zeyuan Zheng, Ming Zhu, Yuning Zou, Pei Liu, Yue Zheng, Xiyuan Yu, Jianzhong Zheng, Chen Shao, Huimin Zhang, Chaoyong Yang   +11 more
wiley   +1 more source

Tensile Properties of Cultured Aortic Smooth Muscle Cells Obtained in a quasi-in situ Tensile Test with Thermoresponsive Gelatin

Journal of Biomechanical Science and Engineering, 2006
We established a quasi-in situ tensile test to measure the tensile properties of smooth muscle cells (SMCs) cultured on substrate maintaining their shape and cytoskeletal integrity.
Kazuaki NAGAYAMA, Akira TSUGAWA, Takeo MATSUMOTO   +2 more
doaj   +1 more source

Semi‐Automated Platform for Early Prenatal Coelocentesis Testing Using Electrospun Nanofiber Technology

Macromolecular Materials and Engineering, Volume 311, Issue 6, June 2026.
A semi‐automated approach for early prenatal diagnosis is developed for low‐cellularity samples from coelocentesis by exploiting biotin/streptavidin interaction to functionalize electrospun mats with antibodies. With potential microfluidic integration, the resulting platform enables fetal cell capture, offering a strategy toward improved efficiency and
Emanuela Muscolino, Anna Barbara Di Stefano, Santina Acuto, Clelia Dispenza   +3 more
wiley   +1 more source

Development of a Microforce Sensor and Its Array Platform for Robotic Cell Microinjection Force Measurement

Sensors, 2016
Robot-assisted cell microinjection, which is precise and can enable a high throughput, is attracting interest from researchers. Conventional probe-type cell microforce sensors have some real-time injection force measurement limitations, which prevent ...
Yu Xie, Yunlei Zhou, Yuzi Lin, Lingyun Wang, Wenming Xi   +4 more
doaj   +1 more source