Results 51 to 60 of about 6,990 (193)

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos

Advanced Science, EarlyView.
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan, Yelian Yan, Yalin Liang, Kanghua Zhong, Zhican Fu, Xiaobo Wang, Chao Liu, Tao Huang, Keliang Wu   +8 more
wiley   +1 more source

Advanced Biological Imaging for Intracellular Micromanipulation: Methods and Applications

Applied Sciences, 2020
Intracellular micromanipulation assisted by robotic systems has valuable applications in biomedical research, such as genetic diagnosis and genome-editing tasks. However, current studies suffer from a low success rate and a large operation damage because
Wendi Gao, Libo Zhao, Zhuangde Jiang, Dong Sun   +3 more
doaj   +1 more source

Drop‐Shaped Optical Microfiber Enabled Biomechanical Sensor

Advanced Science, EarlyView.
A novel microforce sensor based on a drop‐shaped optical microfiber is presented herein, designed to characterize the biomechanical properties of single cells and microscale living organisms, achieving a force resolution of 24 nN. Leveraging its high sensitivity, facile miniaturization, excellent flexibility, and robust mechanical stability, this ...
Yan Xu, Xitao Tu, Haochen Jiang, Jun Mo, Xinyue Zhang, Xiaomin Yue, Limin Tong, Lei Zhang   +7 more
wiley   +1 more source

The Effects of Cold Arm Width and Metal Deposition on the Performance of a U-Beam Electrothermal MEMS Microgripper for Biomedical Applications

Micromachines, 2019
Microelectromechanical systems (MEMS) have established themselves within various fields dominated by high-precision micromanipulation, with the most distinguished sectors being the microassembly, micromanufacturing and biomedical ones.
Marija Cauchi, Ivan Grech, Bertram Mallia, Pierluigi Mollicone, Nicholas Sammut   +4 more
doaj   +1 more source

Autonomous Machine Learning‐Based Classification and Arrangement of Submillimeter Objects Using a Capillary Force Gripper

Advanced Intelligent Discovery, EarlyView.
This study presents an automated system integrating a capillary force gripper and machine learning‐based object detection for sorting and placing submillimeter objects. The system achieved stable and simultaneous manipulation of four object types, with an average task time of 86.0 seconds and a positioning error of 157 ± 84 µm, highlighting its ...
Satoshi Ando, Naoto Watanabe, Chihiro Sekine, Shogen Sekiguchi, Ohmi Fuchiwaki   +4 more
wiley   +1 more source

High-Speed Cell Assembly with Piezo-Driven Two-Finger Microhand

Applied Sciences
In the past few decades, researchers have conducted extensive studies on cell micromanipulation methods. However, there has consistently been a lack of a micromanipulation system that excels in both precision and speed.
Yue Zhao, Yan Deng, Junnan Chen, Masaru Kojima, Qiang Huang, Tatsuo Arai, Xiaoming Liu   +6 more
doaj   +1 more source

Bubbles Acting as Micro End‐Effectors for Dexterous Manipulation and Sensing in Aqueous Environment

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Inspired by bubbles, this article proposes a low‐cost method for multifunctional manipulation and sensing using microbubbles in aqueous environments. Bubbles are easily generated in situ, enabling the safe and adaptive handling of microobjects and sensing of microforces and surface textures.
Zichen Xu, Qingsong Xu
wiley   +1 more source

Towards Advanced Intelligent and Perceptive Soft Grippers

Advanced Intelligent Systems, EarlyView.
Implementing soft yet strong and intelligent soft grippers request innovative and creative solutions in designing soft bodies and seamlessly integrating actuated systems with hierarchical sensing. This review systematically analyses soft grippers with a deep understanding of core components, from fundamental design principles to actuation and sensing ...
Haneul Kim, Hayeon Shin, Seik Park, Changbeom Shim, Seonggun Joe   +4 more
wiley   +1 more source

Automated Shear Strength Characterization at Micro Scales Based on a Microrobotic System

Micromachines
Mechanical properties are critical for characterizing and fabricating advanced materials. While current characterization methods are well-established for the nanoscale and larger millimeter-scale, a significant gap exists in automated testing at the ...
Panbing Wang, Xintao Li, Xinyu Liu
doaj   +1 more source

Development and Hybrid Position/Force Control of a Dual-Drive Macro-Fiber-Composite Microgripper

Sensors, 2018
This paper reports on the development, implementation and hybrid control of a new micro-fiber-composite microgripper with synchronous position and force control capabilities.
Jin Zhang, Yiling Yang, Junqiang Lou, Yanding Wei, Lei Fu   +4 more
doaj   +1 more source