Results 51 to 60 of about 3,891 (209)

Analytical and Simulation-Based Prediction of Surface Roughness for Micromilling Hardened HSS

Journal of Manufacturing and Materials Processing, 2019
The high quality demand for machined functional surfaces of forming tools, entail extensive investigations for the adjustment of the manufacturing process.
Alexander Meijer, Jim A. Bergmann, Eugen Krebs, Dirk Biermann, Petra Wiederkehr   +4 more
doaj   +1 more source

Automated Microfluidic Platform for Single Spheroid Culture and Extracellular Vesicle Isolation: Application to Spheroid Transcriptomic Profiling. [PDF]

Small
An automated microfluidic platform enables single‐spheroid culture, continuous EV collection, and efficient isolation using size filtration and immunomagnetic capture, unlocking spheroid heterogeneity. The system captures CD63/CD81‐positive EVs from individual spheroids with 60% yield. Using adrenocortical carcinoma spheroids, the platform reveals that
Hut M, Denis J, Bottausci F, Cubizolles M, Laurent P, Kaal J, Benessalah M, Boizot F, Cherradi N, Fouillet Y, Agache V.   +10 more
europepmc   +2 more sources

Next generation spindles for micromilling. [PDF]

, 2004
There exists a wide variety of important applications for micro- and meso-scale mechanical systems in the commercial and defense sectors, which require high-strength materials and complex geometries that cannot be produced using current MEMS fabrication technologies.
Pathak, Jay P. (Machine Tool Research Center, University of Florida, Gainesville, FL), Payne, Scott W. T. (Machine Tool Research Center, Gill, David Dennis, Ziegert, John C. (Machine Tool Research Center, Jokiel, Bernhard, Jr.   +10 more
openaire   +2 more sources

Micromilling strategies for machining thin features [PDF]

Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science, 2006
Micromilling of metal structures with ‘thin’ features represents a major challenge towards broadening the use of this technology in a range of microengineering applications, for example in producing multi-channel microstructures, housing for mechanical microdevices, and surgical instruments.
Popov, Krastimir Borisov, Dimov, Stefan Simeonov, Pham, Duc Truong, Ivanov, Atanas   +3 more
openaire   +2 more sources

Experimental study on the milling process of microchannel

Journal of Hebei University of Science and Technology, 2016
In order to improve the milling efficiency of microchannels, the micro milling cutter is proposed to fabricate the microchannel array structures on the aluminum alloy sheet.
Yanxiao XU, Qingfu QIU, Wei ZHOU
doaj   +1 more source

Creating movable interfaces by micro-powder injection moulding [PDF]

, 2013
This paper presents a novel in situ technique to produce articulated components with high-precision, micro-scale movable interfaces by micro-powder injection moulding (μPIM).
Alcock, Jeffrey R., Annicchiarico, Daniele, Attia, Usama M., Hauata, M., Walton, I.   +4 more
core   +1 more source

Workpiece Temperature Investigation In Micromilling of Titanium Alloy

CIRP Journal of Manufacturing Science and Technology, 2021
Abstract The study of the micromachining process of titanium alloys has been intensified due to a greater need to develop microcomponents applied to the medical area. However, the investigation of the behavior of process variables is still incipient, complex and challenging.
Aline Gonçalves dos Santos, Marcio Bacci da Silva, Gustavo Vilela Oliveira, Mark James Jackson   +3 more
openaire   +1 more source

Method for profile reconstruction of the workpiece surface during groove micromilling

Frontiers in Mechanical Engineering
A leading trend in modern industry is hybrid manufacturing methods. The intention is to integrate additive and subtractive methods into a single machine.
Marcin Gołaszewski, Patryk Fiszer, Bartosz Powałka   +2 more
doaj   +1 more source

Micromachining Microchannels on Cyclic Olefin Copolymer (COC) Substrates with the Taguchi Method

Micromachines, 2017
Micromilling is a straightforward approach to the manufacture of polymer microfluidic devices for applications in chemistry and biology. This fabrication process reduces costs, provides a relatively simple user interface, and enables the fabrication of ...
Pin-Chuan Chen, Ren-Hao Zhang, Yingyot Aue-u-lan, Guo-En Chang   +3 more
doaj   +1 more source

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

Advanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source