Results 361 to 370 of about 36,831 (386)
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Advances in Antimicrobial Microneedle Patches for Combating Infections
Advances in Materials, 2020Skin infections caused by bacteria, viruses and fungi are difficult to treat by conventional topical administration because of poor drug penetration across the stratum corneum.
Rezvan Jamaledin +8 more
semanticscholar +1 more source
Multifunctional Silk Fibroin Methacryloyl Microneedle for Diabetic Wound Healing.
Small, 2022Diabetic wound is one of the common complications in diabetic patients, which exhibits chronic, hard-to-heal characteristics. The healing process of wounds is impaired by several factors, including excessive oxidative stress, blocked angiogenesis, and ...
Gaopeng Guan +6 more
semanticscholar +1 more source
Coating Formulations for Microneedles
Pharmaceutical Research, 2007To develop a rational basis for designing coating solution formulations for uniform and thick coatings on microneedles and to identify coating strategies to form composite coatings, deliver liquid formulations, and control the mass deposited on microneedles.Microneedles were fabricated using laser-cutting and then dip-coated using different aqueous ...
Harvinder S. Gill, Mark R. Prausnitz
openaire +2 more sources
Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology, 2003
We have developed arrays of microscopic needles capable of providing pathways for drug delivery across skin without the pain associated with conventional injections. We measured the force to insert microneedles into human subjects and compared it to the force to cause microneedles to break.
Mark R. Prausnitz +2 more
openaire +2 more sources
We have developed arrays of microscopic needles capable of providing pathways for drug delivery across skin without the pain associated with conventional injections. We measured the force to insert microneedles into human subjects and compared it to the force to cause microneedles to break.
Mark R. Prausnitz +2 more
openaire +2 more sources
Microneedling in androgenetic alopecia; comparing two different depths of microneedles
Journal of Cosmetic Dermatology, 2020AbstractBackgroundMicroneedling has shown to have positive therapeutic effects in treatment of androgenetic alopecia (AGA); however, the best microneedling protocol is still controversial.AimsInvestigating effect of microneedling with 2 different depths of penetration on promoting hair growth in patients with AGA.MethodsSixty patients, in the age of 18‐
Gita Faghihi +4 more
openaire +3 more sources
Magneto‐Responsive Microneedle Robots for Intestinal Macromolecule Delivery
Advances in Materials, 2021Oral administration is the most convenient and commonly used approach for drug delivery, while it is still a challenge to overcome the complicated gastrointestinal barriers and realize efficient macromolecular drug absorption.
Xiaoxuan Zhang +4 more
semanticscholar +1 more source
Lab under the Skin: Microneedle Based Wearable Devices
Advanced Healthcare Materials, 2021While the current smartwatches and cellphones can readily track mobility and vital signs, a new generation of wearable devices is rapidly developing to enable users to monitor their health parameters at the molecular level.
H. Teymourian +3 more
semanticscholar +1 more source
Microneedles and transdermal applications
Expert Opinion on Drug Delivery, 2006With the limitations of oral drug delivery and the pain and needle phobias associated with traditional injections, drug delivery research has focused on the transdermal delivery route. A formidable barrier to transdermal drug delivery is the stratum corneum, the superficial layer of the skin.
Dorian Liepmann +2 more
openaire +3 more sources
2010
The application relates to microfluidic needles and their manufacturing methods. The microfluidic needle comprises an interface portion containing at least one fluid communication channel, an elongated needle portion (40) projecting away from the interface portion (44), the needle portion having a tip and sidewalls connecting the tip to the interface ...
Gao, Feng +3 more
openaire
The application relates to microfluidic needles and their manufacturing methods. The microfluidic needle comprises an interface portion containing at least one fluid communication channel, an elongated needle portion (40) projecting away from the interface portion (44), the needle portion having a tip and sidewalls connecting the tip to the interface ...
Gao, Feng +3 more
openaire
Microneedles: Bench to Bedside
Therapeutic Delivery, 2015Microneedles are tiny micron-sized structures, made of a variety of materials, used to minimally disrupt the outermost layer of the skin for enhancing the delivery of therapeutic molecules across the skin. They are sufficiently long enough just to breach the stratum corneum barrier but too short to reach the nerve endings that perceive pain.
openaire +3 more sources