Results 121 to 130 of about 37,259 (377)

Low‐Temperature Fabrication of Thymosin β4‐Loaded Soluble Microneedles to Promote Wound Healing by Specific Binding to Downregulated Immune Regulators Vsig4 and IL22rɑ2

Advanced Healthcare Materials, EarlyView.
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He, Mei Yuan, Changkang Feng, Yixuan Zhang, Jinjing Che   +4 more
wiley   +1 more source

Wearable bio and chemical sensors [PDF]

, 2014
Chemical and biochemical sensors have experienced tremendous growth in the past decade due to advances in material chemistry combined with the emergence of digital communication technologies and wireless sensor networks (WSNs) [1].
Anoshkin, Ataman, Badugu, Bandodkar, Bergmann, Bhandari, Byrne, Chandrasekhar, Chen, Chu, Claramunt, Coyle, Coyle, Coyle, Curto, Curto, Derbyshire, Gerard, Guinovart, Hill, Jia, Khodagholy, Kim, Kinkeldei, Li, Li, Lima, Lobnik, Mannoor, Massie, Miller, Miller, Morris, Nilghaz, Nilghaz, Ohashi, Oncescu, O’Mahony, Papacosta, Patterson, Potyrailo, Rebrin, Reches, Sakaguchi, Schazmann, Strambini, Suzuki, Voirin, Whitesides, Windmiller, Xing, Yang   +51 more
core   +1 more source

Electro‐Stimulated Graphene‐Polymer Nanocomposites Enable Wearable Patches With Feedback‐Controlled Drug Release

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Stimuli‐responsive nanomaterials capable of spatiotemporal control over drug release are of nanocomposite patch (“e‐Medi‐Patch”) engineered from biodegradable polycaprolactone (PCL), graphene nanoplatelets, and a redox‐active therapeutic, niclosamide. The hierarchical composite integrates π‐π interactions between aromatic drug molecules
Santosh K. Misra, Ketan Dighe, Pranay Saha, Teresa Aditya, Muhammad S. Khan, Maha Alafeef, Parikshit Moitra, Dipanjan Pan   +7 more
wiley   +1 more source

Fabrication Technology of Self-Dissolving Sodium Hyaluronate Gels Ultrafine Microneedles for Medical Applications with UV-Curing Gas-Permeable Mold

Gels
Microneedles are of great interest in diverse fields, including cosmetics, drug delivery systems, chromatography, and biological sensing for disease diagnosis.
Rio Yamagishi, Sayaka Miura, Kana Yabu, Mano Ando, Yuna Hachikubo, Yoshiyuki Yokoyama, Kaori Yasuda, Satoshi Takei   +7 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Nanosuspension-Based Dissolving Microneedle Arrays for Intradermal Delivery of Curcumin

Pharmaceutics, 2019
The objective of this study was to evaluate the intradermal delivery of curcumin utilising poly(vinylalcohol) (PVA)-based microneedles loaded with curcumin nanosuspension (CU-NS).
Sharif Abdelghany, Ismaiel A. Tekko, Lalitkumar Vora, Eneko Larrañeta, Andi Dian Permana, Ryan F. Donnelly   +5 more
doaj   +1 more source

Wireless sEMG System with a Microneedle-Based High-Density Electrode Array on a Flexible Substrate [PDF]

, 2019
Surface electromyography (sEMG) signals reflect muscle contraction and hence, can provide information regarding a user's movement intention. High-density sEMG systems have been proposed to measure muscle activity in small areas and to estimate ...
CHA, KYOUNG JE, CHUNG, WAN KYUN, GANG, YONG GU, KIM, DONG SUNG, KIM, MINJAE   +4 more
core   +1 more source

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

Advanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon, Hee Gyeong Ko, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Nayoung Lee, So Won Jeon, Yun‐A Kim, Jong Sang Yoon, Kyung‐Yup Cha, Min‐Ho Kang, Dong Yun Lee, Soo‐Hong Lee, Gi Doo Cha, Kisuk Yang, Donghyun Lim, Heemin Kang, Su Ryon Shin, Han Young Kim, Hyun‐Do Jung   +21 more
wiley   +1 more source

Bioinspired Wet Adhesive Proanthocyanidins Microneedles for Ocular Wound Healing

Research
Microneedles have shown considerable potential in treating ocular diseases, yet enhancing their architecture and functionality to improve therapeutic efficacy poses marked challenges.
Bin Kong, Rui Liu, Tiantian Kong, Yuanjin Zhao   +3 more
doaj   +1 more source

Composite Dissolving Microneedles for Coordinated Control of Antigen and Adjuvant Delivery Kinetics in Transcutaneous Vaccination [PDF]

, 2012
Transcutaneous administration has the potential to improve therapeutics delivery, providing an approach that is safer and more convenient than traditional alternatives, while offering the opportunity for improved therapeutic efficacy through sustained ...
Ai-Ling, Michelle Lim, DeMuth, Peter Charles, Garcia-Beltran, Wilfredo F., Hammond, Paula T, Irvine, Darrell J   +4 more
core   +1 more source