Hyaluronic acid microneedle patch for transdermal delivery of naringin-loaded PEGylated terpesomes in a rat model of rheumatoid arthritis: Modulation TGF-β1, oxidative stress, and inflammation. [PDF]
Elhabal SF +13 more
europepmc +1 more source
The introduction covers the background and significance of conjunctivitis. It continues with a review of etiology, epidemiology, and clinical manifestations. Diagnostic methods are described, followed by discussions on pathophysiology and classification. Current treatment strategies, preventive measures, and therapeutic challenges are analyzed.
Xia Linkang +11 more
wiley +1 more source
Microneedle-based delivery of cell membrane vesicles as IL-17RA decoys for Psoriasis treatment. [PDF]
Tu B +10 more
europepmc +1 more source
Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications
Particle shape is a key design parameter governing biological interactions. Advances in fabrication enable precise control over anisotropy and compartmentalization, allowing modulation of cellular uptake, transport, and biodistribution, ultimately enhancing therapeutic performance. ABSTRACT Polymer geometry is a primary determinant of physical behavior
Francisca G. Perfeito +2 more
wiley +1 more source
Spatiotemporal controlled release of YCM/Cu<sup>2</sup>⁺ hydrogel microneedle system synergistically accelerates chronic wound healing in diabetes. [PDF]
Zhang M +7 more
europepmc +1 more source
Advances in cholesterol and lipoproteins detection for healthcare: A review
Cholesterol is one of the main biomarkers related to the development of cardiovascular diseases. Its detection still relies on traditional methods of analysis, such as gas and liquid chromatographies. Detection of free cholesterol in saliva with redox or enzymatic sensors or detection of lipoproteins in blood with aptamer sensors are currently the most
Jacopo Giaretta +7 more
wiley +1 more source
Microneedle Strategies for Diabetic Wound Management: A Comprehensive Review of Materials, Mechanisms, and Therapeutic Outcomes. [PDF]
Naik K, Singh K.
europepmc +1 more source
Cell membrane‐coated nanoparticles for dermatological diseases
Skin disorders are challenging to treat due to complex barrier functions and limited conventional therapies. Biomimetic cell membrane‐coated nanoparticles (CM‐NPs) offer a superior nanomedicine approach by evading immune detection and enabling precise targeting.
Shuaijun Zou, Baojie Zhang, Yuanjie Zhu
wiley +1 more source
Immunomodulatory microneedles restore mitochondrial homeostasis and balance TGF-β/TNF-α signaling to accelerate diabetic wound repair. [PDF]
Liao M +8 more
europepmc +1 more source

