Results 11 to 20 of about 3,634 (250)

Transepidermal Delivery of Calcium Hydroxyapatite (CaHA) Microneedling: A Novel Approach for Inducing Collagen Types III and IV

Biomedicines
Background/Objectives: Microneedling is increasingly applied to enhance transepidermal drug delivery. Calcium hydroxyapatite (CaHA) has recognized biostimulatory properties, but its delivery and distribution within the dermis remain poorly characterized.
Andréia Luiza Oliveira Costa, Fernando Veloso Caldeira Barcellos, Maria Tereza Scardua Mariano, Eloá Mangabeira Santos, Lorena dos Reis Pereira Queiroz, Erivelton Pereira Santos, Vitória Regina Oliveira de Melo, Sérgio Henrique Sousa Santos, Lucyana Conceição Farias, Alfredo Maurício Batista de Paula, André Luiz Sena Guimarães   +10 more
doaj   +3 more sources

Topical tranexamic acid with microneedling versus microneedling alone in treatment of melasma: clinical, histopathologic, and immunohistochemical study

Journal of the Egyptian Women’s Dermatologic Society, 2019
Background Melasma is an acquired disorder of symmetrical hypermelanosis that involves sun-exposed areas of the skin. Although multiple therapeutic modalities have previously been tried, successful, truly effective treatment options for this condition ...
Fatma Y Saleh, Eman S Abdel-Azim, Maha H Ragaie, Mary G Guendy   +3 more
doaj   +2 more sources

Microneedling: a review [PDF]

Revista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Sugery, 2020
Introduction: Microneedling, also called percutaneous collagen induction therapy (PCIT), is a technique applied with an equipment called roller. It is suitable for rejuvenation, alopecia, all types of scars, acne, photo rejuvenation, stretch marks, skin flaccidity, melasma, expression wrinkles, and improvement of the general aspect of the skin ...
Adriana Da Silva Ferreira, Daniella Leiros Aita, Meire Aparecida Muneratto   +2 more
openaire   +3 more sources

Study to determine the safety and efficacy of microneedling as an effective treatment for acne vulgaris

Skin Health and Disease, 2023
Background Acne is an inflammatory disease of the pilosebaceous unit that occurs primarily in adolescents. There is no current ideal treatment for acne vulgaris, as many mainstay prescription treatment modalities can compromise the skin microbiome or ...
Mona L. Alqam, Brian C. Jones, Thomas M. Hitchcock   +2 more
doaj   +2 more sources

Efficacy of Autologous Injectable Platelet Rich Fibrin in Facial Atrophic Acne Scars in Combination with Microneedling: A Randomized Clinical Trial

Nepal Journal of Dermatology, Venereology & Leprology
Introduction: Several modalities for treating acne scars exist. The combination of microneedling and injectable platelet-rich fibrin (i-PRF) is a synergistic approach.
Katyayani Pandey, Sudha Agrawal, Prajwal Pandey   +2 more
doaj   +5 more sources

Comparative Evaluation of the Therapeutic Efficacy of Microneedling Alone or Microneedling Combined with Topical 5-Fluorouracil In Localized Stable Childhood Vitiligo

Advances in Human Biology, 2016
Aim: The aim of this study was to evaluate and compare the therapeutic efficacy of microneedling and microneedling combined with topical 5- fluorouracil. Materials and Method: Twentyfive patients with localized stable vitiligo were treated in each group.
B C Ghiya, Prasoon Soni, Ankit Kumar Singrodia, Sunny Chhabra, R D Mehta, Jyoti S Bai   +5 more
doaj   +1 more source

Microneedling-assisted delivery of metformin versus tranexamic acid in treating melasma: a randomized controlled study

European Journal of Medical Research
Background Melasma is a common, relapsing hyperpigmentation disorder with limited long-term treatment success. Recent advances suggest that microneedling may enhance the transdermal delivery and efficacy of topical agents.
Abdelshakour Al Mohammady, Ahmed S. Kadah, Mohamed A. Mahran, Mohamed L. Elsaie   +3 more
doaj   +2 more sources

Evaluation of the effectiveness of microneedling with tranexamic acid in comparison with microneedling with vitamin C in the treatment of melasma: A prospective and single‐blind clinical trial

Health Science Reports, 2023
Background and Aims Melasma is a common skin condition. Microneedling acts as a dermal delivery system that facilitates the penetration of lightening agents such as vitamin C and tranexamic acid (TXA) into the deeper layers of the skin.
Nader Pazyar, Maryam Raeispour, Reza Yaghoobi, Maryam Seyedtabib   +3 more
doaj   +2 more sources

Microneedling in Abdominal Scarring after DIEP-flap Breast Reconstruction to Improve Scar Quality: A Randomized Controlled Split Scar Trial

Plastic and Reconstructive Surgery, Global Open
Background:. Deep inferior epigastric perforator (DIEP) flap breast reconstruction leads to large scars in the breast and abdominal region. Common symptoms related to abdominal scarring include changes in color, stiffness, thickness, and irregularity of ...
Kristel E. Everaars, MSc, Audrey M. Meulendijks, PhD, Esther P.M. Tjin, PhD, Anne M. Eskes, PhD, Stefan Hummelink, PhD, Erik H. de Laat, PhD, Dietmar J.O. Ulrich, MD, PhD   +6 more
doaj   +2 more sources

Effects of CE Ferulic^® Combined with Microneedling in the Treatment of Pigmentary Disorders: A Monocentric, Split Face, Comparative Study

Cosmetics
Pigmentary disorders of the face present a significant challenge in dermatology, impacting the confidence and well-being of affected individuals. Various approaches have been developed to address these concerns, including microneedling and topical ...
Ilaria Proietti, Stefania Guida, Agnieszka Dybala, Alessandra Spagnoli, Concetta Potenza   +4 more
doaj   +2 more sources