Results 21 to 30 of about 2,229 (188)

Fabrication of Microneedles

2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, 2007
This research paper was performed to study and utilizes two kinds of materials which match with two different fabrications in order to design an ideal shape of microneedles. The technology employs the polymer microneedles and the silicon microneedles with the height of 236 mum and 350 mum respectively.
Yu-Tang Chen, Chin-Chun Hsu, Chieh-Hsiu Tsai, Shung-Wen Kang   +3 more
openaire   +2 more sources

Effectiveness Evaluation of Microneedling Therapy for Diabetic Ulcer: An Animal Model Study

Plastic and Reconstructive Surgery, Global Open
Background:. Diabetic ulcer is an intractable complication seen in nearly 6% of diabetes patients. Some patients with diabetic ulcers cannot avoid femoral amputation by the current standard treatments.
Eri Morinaga, MD, Naoaki Sakata, MD, Ryo Kawakami, MSc, Reiko Naito, MD, Gumpei Yoshimatsu, MD, Satoshi Takagi, MD, Shohta Kodama, MD   +6 more
doaj   +1 more source

Microneedles

Biomaterials Science, 2023
Wound management is a serious concern worldwide, inflicting a huge social and economic burden on patients and healthcare systems, and research into efficient wound-management measures is crucial. Although advances have been made in traditional wound dressings for wound management to date, the complicated environment near the wound leads to inadequate ...
Zhao, Ze Qiang, Liang, Ling, Jing, Li Yue, Liu, Yue, Zhang, Yu Han, Shahbazi, Mohammad-Ali, Chen, Bo Zhi, Guo, Xin Dong   +7 more
  +5 more sources

Efficacy of Microneedling Combined with 30% Salicylic Acid Peel Versus Microneedling Alone in the Treatment of Post Acne Scar: A Clinical Trial

Advanced Medical Journal
Background and objective: Acne scarring is a common problem with several treatment options available including microneedling, chemical peels and lasers. This study compares the efficacy of microneedling combined with 30% salicylic acid peel versus micro
Wafa Kamal Hama Rahim, Ali Mozan Dhahir Elethawi   +1 more
doaj   +1 more source

Topical tranexamic acid with microneedling versus microneedling alone in treatment of melasma: clinical, histopathologic, and immunohistochemical study

Journal of the Egyptian Women’s Dermatologic Society, 2019
Background Melasma is an acquired disorder of symmetrical hypermelanosis that involves sun-exposed areas of the skin. Although multiple therapeutic modalities have previously been tried, successful, truly effective treatment options for this condition ...
Fatma Y Saleh, Eman S Abdel-Azim, Maha H Ragaie, Mary G Guendy   +3 more
doaj   +1 more source

Transepidermal Delivery of Triamcinolone Acetonide or Platelet Rich Plasma using either Fractional Carbon Dioxide Laser or Microneedling in Treatment of Alopecia Areata

Dermatology Practical & Conceptual, 2022
Introduction: Transepidermal drug delivery,  using “laser-assisted drug delivery'', or microneedling, are new treatment modalities, that can improve drug penetration into skin in treatment of alopecia areata patients. Objective: To evaluate the use of
Khaled El Mulla, Eman Elmorsy, Dalia Halwag, Eman Hassan   +3 more
doaj   +1 more source

Microneedling with dermaroller

Journal of Cutaneous and Aesthetic Surgery, 2009
Microneedling with dermaroller is a new treatment modality for the treatment of scars, especially acne scars, stretch marks, wrinkles, and for facial rejuvenation. It is a simple and relatively cheap modality that also can be used for transdermal drug delivery.
openaire   +2 more sources

Microneedle Radiofrequency

Facial Plastic Surgery Clinics of North America, 2020
Microneedle radiofrequency (RF) is a breakthrough in targeting skin laxity and rhytids that provides direct in situ delivery, impedance measurements, temperature measurements, energy delivery controls, and targeting of various skin depths to achieve desired clinical outcomes.
openaire   +3 more sources

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

Advanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang, Xiaoyan Li, Xiao Xu, Kelun Zhang, Fengjiao Yu, Zhen Shang, Nailong Pan, Junlin Lv, Yiwei Xu, Yan Tang, Liang Zhang, Xiaotong Li, Taoyi Wang, Jing Tao, Jiaxu Song, Mengyu Zhang, Xin Ma, Dan Han, Xiaoying Kong, Wenhua Xu   +19 more
wiley   +1 more source