Results 201 to 210 of about 48,051 (246)

Micronucleus formation in human cancer cells is biased by chromosome size [PDF]

Genes, Chromosomes and Cancer, 2019
Chromosomal instability is one of the hallmarks of cancer and caused by chromosome missegregation during mitosis, a process frequently associated with micronucleus formation.
T. Bochtler, Mutlu Kartal-Kaess, M. Granzow, T. Hielscher, M. R. Cosenza, C. Herold-Mende, A. Jauch, A. Krämer   +7 more
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The micronucleus test

Mutation Research - Environmental Mutagenesis and Related Subjects Including Methodology, 1975
W. Schmid
exaly   +2 more sources

Using the comet and micronucleus assays for genotoxicity studies: A review

Biomedicine and Pharmacotherapy, 2015
Rodrigo Pinheiro Araldi, Rodrigo Franco De Carvalho, Thatiana Corrêa De Melo   +2 more
exaly   +2 more sources

Recommendations and quality criteria for micronucleus studies with humans.

Mutation research. Reviews in mutation research, 2021
Micronucleus (MN) analyses in peripheral blood lymphocytes and exfoliated cells from different organs (mouth, nose, bladder and cervix) are at present the most widely used approaches to detect damage of genetic material in humans. MN are extranuclear DNA-
A. Nersesyan, M. Kundi, M. Fenech, H. Stopper, J. D. da Silva, C. Bolognesi, M. Mišík, S. Knasmueller   +7 more
semanticscholar   +1 more source

Micronucleus test in tadpole erythrocytes: Trends in studies and new paths.

Chemosphere, 2020
The micronucleus test has been applied for more than three decades in tadpoles, generating an early warning of environmental quality. In this study, we reviewed 48 articles on the micronucleus test in tadpoles, published between 1987 and 2018.
Marcelino Benvindo-Souza, Eliane Andreia Santos Oliveira, R. A. Assis, Cirley Gomes Araújo Santos, R. E. Borges, D. de Melo e Silva, Lia Raquel de Souza Santos   +6 more
semanticscholar   +1 more source

Micronucleus Test Reveals Genotoxic Effects in Bats Associated with Agricultural Activity

Environmental Toxicology and Chemistry, 2020
Bats play a vital role in our ecosystems and economies as natural pest‐control agents, seed dispersers, and pollinators. Agricultural intensification, however, can impact bats foraging near crops, affecting the ecosystem services they provide.
N. Sandoval-Herrera, Jesusa Paz Castillo, L. G. H. Montalvo, Kenneth C. Welch   +3 more
semanticscholar   +1 more source

New in silico models to predict in vitro micronucleus induction as marker of genotoxicity.

Journal of Hazardous Materials, 2019
The evaluation of genotoxicity is a fundamental part of the safety assessment of chemicals due to the relevance of the potential health effects of genotoxicants. Among the testing methods available, the in vitro micronucleus assay with mammalian cells is
D. Baderna, D. Gadaleta, Eleonora Lostaglio, G. Selvestrel, G. Raitano, A. Golbamaki, A. Lombardo, E. Benfenati   +7 more
semanticscholar   +1 more source

Molecular cytogenetics of the micronucleus: Still surprising.

Mutation Research. Genetic Toxicology and Environmental Mutagenesis, 2018
The purpose of this review is to provide an historical overview of the molecular cytogenetic approaches that have been pursed to identify the mechanism of origin of micronuclei as well as highlight the significance of the findings obtained for the ...
A. Russo, F. Degrassi
semanticscholar   +1 more source

The in vitro micronucleus technique.

Mutation research, 2000
M. Fenech
semanticscholar   +1 more source