Results 1 to 10 of about 193,911 (249)

A Vaccine with Multiple Receptor-Binding Domain Subunit Mutations Induces Broad-Spectrum Immune Response against SARS-CoV-2 Variants of Concern

Vaccines, 2022
With the emergence of more variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the immune evasion of these variants from existing vaccines, the development of broad-spectrum vaccines is urgently needed. In this study, we designed
Xu-Chen Hou, Hui-Fang Xu, Yang Liu, Peng Sun, Lin-Wei Ding, Jun-Jie Yue, Tian-Tian Wang, Xin Gong, Jun Wu, Bo Liu   +9 more
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A Delta–Omicron Bivalent Subunit Vaccine Elicited Antibody Responses in Mice against Both Ancestral and Variant Strains of SARS-CoV-2

Vaccines, 2023
Continued mutation of the SARS-CoV-2 genome has led to multiple waves of COVID-19 infections, and new variants have continued to emerge and dominate. The emergence of Omicron and its subvariants has substantially increased the infectivity of SARS-CoV-2 ...
Tiantian Wang, Jing Zheng, Huifang Xu, Zhongyi Wang, Peng Sun, Xuchen Hou, Xin Gong, Bin Zhang, Jun Wu, Bo Liu   +9 more
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Antioxidant and Immunomodulatory Activities of Polysaccharides from Fermented Wheat Products of Grifola frondosa: In Vitro Methods

International Journal of Food Science, 2023
Despite the well-known health benefits of Grifola frondosa, there is a lack of understanding regarding the potential antioxidant and immunomodulatory properties of different varieties when fermented with wheat grains. We aimed to explore the potential of
Xiaoqing Xu, Ying Liu, Chunli Pan, Shaoliang Han, Lan Ma, Yu Qiao, Bo Shi, Qing Peng   +7 more
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Novel Japanese encephalitis virus NS1-based vaccine: Truncated NS1 fused with E. coli heat labile enterotoxin B subunit

EBioMedicine, 2021
Background: Current vaccines against Japanese encephalitis virus (JEV) of flaviviruses have some disadvantages, such as the risk of virulent reversion. Non-structural protein NS1 is conserved among flaviviruses and confers immune protection without the ...
Jiawu Wan, Ting Wang, Jing Xu, Tao Ouyang, Qianruo Wang, Yanni Zhang, Shiqi Weng, Yihan Li, Yu Wang, Xiu Xin, Xiaoling Wang, Sha Li, Lingbao Kong   +12 more
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X-Chromosome Inactivation and Related Diseases

Genetics Research, 2022
X-chromosome inactivation (XCI) is the form of dosage compensation in mammalian female cells to balance X-linked gene expression levels of the two sexes.
Zhuo Sun, Jinbo Fan, Yang Wang
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Cultural Characteristics and Fruiting-body Productivity of New Cultivar ‘Hwadam’ (Lentinula edodes) by Punching Treatments on the Sawdust Medium

한국균학회지, 2021
표고 ‘화담’의 톱밥배지 안정생산을 위해 침공처리가 균사배양 및 자실체 생산성에 미치는 영향을 조사하였다. 종균 접종후 배지 온도는 배양 23일에 27.0-28.8℃, CO2농도는 배양 16일에 14.0-15.6%까지 높아진 후 감소하였고, O2농도는 CO2농도와 반대의 경향이었다. 배양기간중 침공횟수가 많을수록 배지의 명도(L값)는 감소하고, 색차(ΔE)와 중량감모율은 증가하였다.
Jeong-Han Kim, Jun-Yeong Choi, Yeon-Jin Kim, Ji-Young Mun, Tai-Moon Ha, Gu-Hyun Jung   +5 more
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A Vaccine Based on the Receptor-Binding Domain of the Spike Protein Expressed in Glycoengineered Pichia pastoris Targeting SARS-CoV-2 Stimulates Neutralizing and Protective Antibody Responses

Engineering, 2022
In 2020 and 2021, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, caused a global pandemic. Vaccines are expected to reduce the pressure of prevention and control, and have become the most effective strategy to solve ...
Bo Liu, Ying Yin, Yuxiao Liu, Tiantian Wang, Peng Sun, Yangqin Ou, Xin Gong, Xuchen Hou, Jun Zhang, Hongguang Ren, Shiqiang Luo, Qian Ke, Yongming Yao, Junjie Xu, Jun Wu   +14 more
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Comparison of Mycelial Growth Characteristics According to Culture Conditions of Ulleungdo Collection Strains

한국균학회지, 2020
The collection of biological data of indigenous species must comply with the Nagoya Protocol. Fungi contain various bioactive substances making them an attractive source of several products, including food and medicines.
Minkyeong Kim, Chorong Ahn, Changmu Kim   +2 more
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Regulation of β-Disaccharide Accumulation by β-Glucosidase Inhibitors to Enhance Cellulase Production in Trichoderma reesei

Fermentation, 2022
Trichoderma reesei is a high-yield producer of cellulase for applications in lignocellulosic biomass conversion, but its cellulase production requires induction.
Tingting Long, Peng Zhang, Jingze Yu, Yushan Gao, Xiaoqin Ran, Yonghao Li   +5 more
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Zygotorulaspora cornina sp. nov. and Zygotorulaspora smilacis sp. nov., Two Novel Ascomycetous Yeast Species Isolated from Plant Flowers and Fruits

Mycobiology, 2021
Three isolates belonging to the ascomycetous genus Zygotorulaspora were obtained from the fruits of Cornus officinalis and Smilax china, and flowers of Dendranthema zawadskii var. latilobum in Gongju-si, Korea.
Chorong Ahn, Minkyeong Kim, Changmu Kim
doaj   +1 more source