Results 41 to 50 of about 3,326 (174)

Plasma and Urine Metabolites Associated with Microperimetric Retinal Sensitivity in Age-Related Macular Degeneration

Metabolites
Background: Best-corrected visual acuity (BCVA) is the current gold standard of retinal function measurement but is not affected in early and intermediate forms of age-related macular degeneration (AMD).
Krupa Sourirajan, Kevin Mendez, Ines Lains, Gregory Tsougranis, Haemin Kang, Georgiy Kozak, Augustine Bannerman, Roshni Bhat, Hanna Choi, Archana Nigalye, Ivana K. Kim, Demetrios G. Vavvas, David M. Wu, Liming Liang, John B. Miller, Joan W. Miller, Jessica Lasky-Su, Deeba Husain   +17 more
doaj   +1 more source

CRB1‐Associated Inherited Retinal Dystrophies: Prospective Natural History Study With 4 Years of Follow‐Up

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background The lack of validated and sensitive clinical endpoints remains a major challenge in the design of gene therapy trials for inherited retinal dystrophies (IRDs). This prospective longitudinal cohort study describes the natural disease progression of IRDs caused by pathogenic mutations in the Crumbs homologue 1 (CRB1) gene, and ...
Jessica S. Karuntu, Xuan‐Thanh‐An Nguyen, Mays Talib, Mary J. van Schooneveld, Jan Wijnholds, Maria M. van Genderen, Jos Twisk, Nicoline E. Schalij‐Delfos, Caroline C. W. Klaver, Ralph J. Florijn, Jacoline B. ten Brink, Magda A. Smoor, L. Ingeborgh van den Born, Carel B. Hoyng, Alberta A. H. J. Thiadens, Camiel J. F. Boon   +15 more
wiley   +1 more source

Visual Acuity, Retinal Sensitivity, and Macular Thickness Changes in Diabetic Patients without Diabetic Retinopathy after Cataract Surgery

Journal of Diabetes Research, 2017
Aim. Functional and morphological macular study after cataract surgery in a group of diabetics without diabetic retinopathy compared to nondiabetics to evaluate the effect of surgical oxidative stress on diabetic retina. Methods. Prospective, comparative
Spela Stunf Pukl, Nataša Vidović Valentinčič, Mojca Urbančič, Irena Irman Grčar, Rok Grčar, Vladimir Pfeifer, Mojca Globočnik Petrovič   +6 more
doaj   +1 more source

Randomised Clinical Trial to Evaluate the Efficacy of Acetazolamide for the Treatment of Cystoid Fluid Collections in X‐Linked Retinoschisis: The AXIS Trial

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background This trial aimed to evaluate the efficacy of oral acetazolamide in reducing cystoid fluid collections (CFC) and improving visual function in patients with X‐linked retinoschisis (XLRS). Methods In this investigator‐initiated, single centre, open‐label, randomised controlled trial, XLRS patients aged ≥ 12 years with fovea‐involving ...
Jonathan Hensman, Hind Almushattat, Roselie M. H. Diederen, Tien‐En Tan, Peilun Dai, Coen de Vente, Daniel S. W. Ting, Maria M. van Genderen, Jeannette Ossewaarde‐van Norel, Redmer van Leeuwen, Martha J. H. Tjon‐Fo‐Sang, Clara I. Sánchez, M. Dominik Fischer, Maximilian Pfau, Jos W. R. Twisk, Camiel J. F. Boon   +15 more
wiley   +1 more source

Comparison of efficacy and safety of the combined laser treatment technology versus conventional laser photocoagulation in diabetic macular edema management

Сахарный диабет, 2017
Aim. To evaluate the efficacy and safety of the novel combined laser treatment technology compared with those of the conventional laser photocoagulation in diabetic macular oedema management. Material and methods.
Aleksander Victorovich Doga, Galina Fedorovna Kachalina, Elena Konstantinovna Pedanova, Dmitry Anatolievich Buryakov   +3 more
doaj   +1 more source

Premium Intraocular Lens Selection in Patients With Glaucoma: A Clinical Review

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Glaucoma frequently coexists with cataract, but glaucomatous functional loss, ocular‐surface disease, anatomical abnormalities, and treatment‐related refractive variability may reduce tolerance of premium intraocular lenses. This narrative review critically appraises evidence relevant to lens selection in glaucoma. Central visual‐field status,
Zhihao Liu, Yajuan Zheng, Mingxuan Wang, Jing Zhao   +3 more
wiley   +1 more source

Current Clinical Application of Microperimetry: A Review [PDF]

Seminars in Ophthalmology, 2017
Microperimetry (MP) is a technology that allows the study of retinal sensitivity at different foveal and parafoveal areas as well as eye fixation. It is a technique of functional evaluation, providing a direct correlation between anatomical and functional outcomes.
Molina-Martín, Ainhoa, Pérez Cambrodí, Rafael J., Piñero, David P.   +2 more
openaire   +3 more sources

Microperimetry

Güncel Retina Dergisi (Current Retina Journal), 2017
The rapid progress in retinal diagnostic technologies has positively modified our approach to retinal disorders. One of these approaches is microperimetry. Microperimetry has the ability to overlay a perimetric retinal sensitivity map on fundus photographs allowing better localization of the pathology.
openaire   +1 more source

Evaluating the reliability of a microperimetry-based method for assessing visual function in the junctional zone of geographic atrophy lesions

International Journal of Retina and Vitreous
Purpose To assess the repeatability of a microperimetry methodology for quantifying visual function changes in the junctional zone of eyes with geographic atrophy (GA) in the clinical trial context. Methods A post hoc analysis of the OAKS phase III trial
A. Yasin Alibhai, Eric M. Moult, Muhammad Usman Jamil, Khadija Raza, Marco U. Morales, Ramiro Ribeiro, Caroline R. Baumal, James G. Fujimoto, Nadia K. Waheed   +8 more
doaj   +1 more source

A structure-function correlation between vessel density on OCTA and macular sensitivity on microperimetry in sickle cell retinopathy in children, adolescents, and young adults

AJO International
Background: To identify associations between microvascular changes and functional macular sensitivity in children, adolescents, and young adults with sickle cell disease (SCD).
Naira Ikram, Francisco Altamirano, Celine Chaaya, Hanna De Bruyn, Sandra Hoyek, Inès Fenniri, Osama Sorour, Anne Fulton, Pablo Altschwager, Efren Gonzalez, Nimesh A. Patel   +10 more
doaj   +1 more source