Results 51 to 60 of about 4,392 (201)

Plasma and Urine Metabolites Associated with Microperimetric Retinal Sensitivity in Age-Related Macular Degeneration

Metabolites
Background: Best-corrected visual acuity (BCVA) is the current gold standard of retinal function measurement but is not affected in early and intermediate forms of age-related macular degeneration (AMD).
Krupa Sourirajan, Kevin Mendez, Ines Lains, Gregory Tsougranis, Haemin Kang, Georgiy Kozak, Augustine Bannerman, Roshni Bhat, Hanna Choi, Archana Nigalye, Ivana K. Kim, Demetrios G. Vavvas, David M. Wu, Liming Liang, John B. Miller, Joan W. Miller, Jessica Lasky-Su, Deeba Husain   +17 more
doaj   +1 more source

CRB1‐Associated Inherited Retinal Dystrophies: Prospective Natural History Study With 4 Years of Follow‐Up

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background The lack of validated and sensitive clinical endpoints remains a major challenge in the design of gene therapy trials for inherited retinal dystrophies (IRDs). This prospective longitudinal cohort study describes the natural disease progression of IRDs caused by pathogenic mutations in the Crumbs homologue 1 (CRB1) gene, and ...
Jessica S. Karuntu, Xuan‐Thanh‐An Nguyen, Mays Talib, Mary J. van Schooneveld, Jan Wijnholds, Maria M. van Genderen, Jos Twisk, Nicoline E. Schalij‐Delfos, Caroline C. W. Klaver, Ralph J. Florijn, Jacoline B. ten Brink, Magda A. Smoor, L. Ingeborgh van den Born, Carel B. Hoyng, Alberta A. H. J. Thiadens, Camiel J. F. Boon   +15 more
wiley   +1 more source

Microperimetry and mfERG as functional measurements in diabetic macular oedema undergoing intravitreal ranibizumab treatment [PDF]

, 2020
To evaluate Microperimetry (MP) and multifocal electroretinogram (mfERG) as whole-macula functional markers of treatment response in naive diabetic macular oedema (DMO) patients undergoing ranibizumab treatment.
José Cunha-Vaz, Figueira, João, Miguel Raimundo, João Figueira, Dalila Alves, Ana Rita Santos, Santos, Ana Rita, Cunha-Vaz, José, Raimundo, Miguel, Pestana, Sérgio, Silva, Rufino, Alves, Dalila, Lopes, Marta, Marta Lopes, Rufino Silva, Sérgio Pestana   +15 more
core   +1 more source

Visual Acuity, Retinal Sensitivity, and Macular Thickness Changes in Diabetic Patients without Diabetic Retinopathy after Cataract Surgery

Journal of Diabetes Research, 2017
Aim. Functional and morphological macular study after cataract surgery in a group of diabetics without diabetic retinopathy compared to nondiabetics to evaluate the effect of surgical oxidative stress on diabetic retina. Methods. Prospective, comparative
Spela Stunf Pukl, Nataša Vidović Valentinčič, Mojca Urbančič, Irena Irman Grčar, Rok Grčar, Vladimir Pfeifer, Mojca Globočnik Petrovič   +6 more
doaj   +1 more source

Comparison of efficacy and safety of the combined laser treatment technology versus conventional laser photocoagulation in diabetic macular edema management

Сахарный диабет, 2017
Aim. To evaluate the efficacy and safety of the novel combined laser treatment technology compared with those of the conventional laser photocoagulation in diabetic macular oedema management. Material and methods.
Aleksander Victorovich Doga, Galina Fedorovna Kachalina, Elena Konstantinovna Pedanova, Dmitry Anatolievich Buryakov   +3 more
doaj   +1 more source

Current Clinical Application of Microperimetry: A Review [PDF]

Seminars in Ophthalmology, 2017
Microperimetry (MP) is a technology that allows the study of retinal sensitivity at different foveal and parafoveal areas as well as eye fixation. It is a technique of functional evaluation, providing a direct correlation between anatomical and functional outcomes.
Molina-Martín, Ainhoa, Pérez Cambrodí, Rafael J., Piñero, David P.   +2 more
openaire   +3 more sources

Long‐term follow‐up of chronic central serous chorioretinopathy patients receiving oral eplerenone and half‐dose photodynamic therapy in the SPECTRA trial: SPECTRA trial report No. 4

Acta Ophthalmologica, Volume 104, Issue 5, Page e565-e577, August 2026.
Abstract Purpose Assessing the 24‐month treatment outcome of half‐dose photodynamic therapy (PDT) or oral eplerenone in chronic central serous chorioretinopathy (cCSC). Methods Multicentre randomized clinical trial included cCSC patients from the SPECTRA trial who were randomized to receive half‐dose PDT or oral eplerenone.
Helena M. A. Feenstra, Issam El Mansori, Thomas J. van Rijssen, Roula Tsonaka, Roselie M. H. Diederen, Carel B. Hoyng, Reinier O. Schlingemann, Camiel J. F. Boon, Elon H. C. van Dijk   +8 more
wiley   +1 more source

Two-Photon Microperimetry: A Media Opacity-Independent Retinal Function Assay. [PDF]

, 2021
PurposeCompare results obtained using infrared two-photon microperimetry (2PM-IR) with conventional visual function tests in healthy subjects of varying ages with and without simulated media opacities.MethodsSubjects from two separate cohort studies ...
Palma, Anton M, Browne, Andrew W, Le, Bryan, Nguyen, Kevin, Chang, Steven Yone-Shun, Hussey, Vincent M, Palczewska, Grazyna, Hoffmann, Luke E, Mehta, Urmi V, Wei, Ang, Diep, Anna   +10 more
core   +1 more source

Microperimetry and fundus autofluorescence in patients with early age-related macular degeneration [PDF]

, 2007
Background: Early age-related macular degeneration (AMD) has been correlated with different functional alterations, but the exact relationship between fundus lesions and overlying sensitivity is not well known. The aim of this study was to compare fundus-
Vujosevic S., Convento E., Cavarzeran F., Pitotto E., Midena E., Manfre' A.   +5 more
core   +3 more sources

Evaluating the reliability of a microperimetry-based method for assessing visual function in the junctional zone of geographic atrophy lesions

International Journal of Retina and Vitreous
Purpose To assess the repeatability of a microperimetry methodology for quantifying visual function changes in the junctional zone of eyes with geographic atrophy (GA) in the clinical trial context. Methods A post hoc analysis of the OAKS phase III trial
A. Yasin Alibhai, Eric M. Moult, Muhammad Usman Jamil, Khadija Raza, Marco U. Morales, Ramiro Ribeiro, Caroline R. Baumal, James G. Fujimoto, Nadia K. Waheed   +8 more
doaj   +1 more source