Results 171 to 180 of about 24,554,140 (185)
Some of the next articles are maybe not open access.

Microphysiological Systems: A Cellular Dilemma

2021
Presentation to the Microphysiological Systems (MPS) Webinar: Bridging Human and Animal Research January ...
openaire   +1 more source

Opportunities for Microphysiological Systems in Toxicity Testing of New Drug Modalities.

Annual Review of Pharmacology and Toxicology
New drug modalities offer life-saving benefits for patients through access to previously undruggable targets. Yet these modalities pose a challenge for the pharmaceutical industry, as side effects are complex, unpredictable, and often uniquely human ...
Tengku Ibrahim Maulana   +10 more
semanticscholar   +1 more source

Considerations from the pharmaceutical industry (IQ MPS affiliate) workshop on animal microphysiological systems and 3Rs in drug development.

ALTEX
Most complex in vitro models (CIVM) and microphysiological systems (MPS) are composed of human cells, with the goal of evaluating diseases, efficacy, safety, and pharmacokinetic questions specifically for humans.
Patrick J Devine   +33 more
semanticscholar   +1 more source

Placental microphysiological systems: new advances on promising platforms that mimic the microenvironment of the human placenta.

Lab on a Chip
One of the most complex human physiological processes to study is pregnancy. Standard animal models, as well as two-dimensional models, lack the complexity and biological relevance required to accurately study such a physiological process. Recent studies
Inês M. Gonçalves   +8 more
semanticscholar   +1 more source

The potential of neural microphysiological systems (MPS)

Folia Pharmacologica Japonica
In vitro compound evaluation using human-derived neural cells is beginning to incorporate microphysiological systems (MPS). Neural MPS includes not only microfluidic devices but has also recently recognized neural organoids as viable MPS platforms. The history of neural MPS utilizing microfluidic devices is extensive, with the development of models ...
openaire   +2 more sources

Microphysiological Models of the Respiratory System

2019
The lung is an essential organ that shows remarkable complexity in its structure, environment, and function. Mimicking this dynamic and complex organ in experimental model systems remains a major challenge in biomedical research. Here we review recent research efforts directed towards leveraging microfluidic cell culture techniques to develop ...
openaire   +1 more source

Standardizing designed and emergent quantitative features in microphysiological systems

Nature Biomedical Engineering
Dennis M. Nahon   +32 more
semanticscholar   +1 more source

Should culture media for microphysiological systems be nutritionally physiological?

Nature Reviews Bioengineering
Alastair G. Stewart   +2 more
semanticscholar   +1 more source

Nephrotoxicity Assessment on a microphysiological system

The Proceedings of Mechanical Engineering Congress, Japan, 2021
Tomomi KANEKO-GOTO   +5 more
openaire   +1 more source

Home - About - Disclaimer - Privacy