Results 251 to 260 of about 22,552 (272)

Expression of Microrna-210 and the Prognosis in Glioma Patients: A Meta-Analysis

Biomarkers in Medicine, 2020
Aim: To evaluate the predictive power of tumor microRNA-210 (miR-210) on overall survival (OS) in glioma patients. Materials & methods: Studies were identified through searching PubMed, Embase and China National Knowledge Internet electronic databases.
Pengfei Yan, Fangcheng Zhang
exaly   +3 more sources

Prognostic evaluation of microRNA-210 expression in pediatric osteosarcoma

Medical Oncology, 2013
MicroRNA-210 (miR-210) plays important roles in the regulation of cell growth, angiogenesis, and apoptosis in different cancer type. Previous study of miRNA expression profiling found that miR-210 was significantly elevated in osteosarcoma samples. However, its roles in this disease have not been fully elucidated.
Haiqing, Cai, Lijun, Lin, Haikang, Cai, Mingjie, Tang, Zhigang, Wang   +4 more
openaire   +2 more sources

MicroRNA‐210 is increased and it is required for dedifferentiation of osteosarcoma cell line

Cell Biology International, 2017
AbstractOsteosarcoma (OS) is the most common malignant bone tumor and is prevalent in adolescents. In clinical studies, miR‐210 has been reported to be tightly correlated to the poor prognosis of OS. Nevertheless, its roles in OS have not been fully elucidated.
Haixia, Zhang, Qing, Mai, Juntao, Chen
openaire   +2 more sources

Administration of MicroRNA-210 Promotes Spinal Cord Regeneration in Mice

Spine, 2014
Experimental animal study of treatment of spinal cord injury (SCI).To investigate the therapeutic effects of administering microRNA-210 (miR-210) to promote angiogenesis in a mouse SCI model.Despite many previous studies regarding SCI, there is no established treatment in clinical practice.
Satoshi, Ujigo, Naosuke, Kamei, Hikmat, Hadoush, Yuki, Fujioka, Shigeru, Miyaki, Tomoyuki, Nakasa, Nobuhiro, Tanaka, Kazuyoshi, Nakanishi, Akiko, Eguchi, Toru, Sunagawa, Mitsuo, Ochi   +10 more
openaire   +2 more sources

Effect of MicroRNA-210 on the Growth of Ovarian Cancer Cells and the Efficacy of Radiotherapy

Gynecologic and Obstetric Investigation, 2020
<b><i>Objective:</i></b> The objective of this study is to explore the role of miR-210 in the growth of ovarian cancer cells and the correlation with radiotherapy and to elucidate underlying molecular mechanisms. <b><i>Methods:</i></b> Human ovarian cancer cell lines OVCAR3 and SKOV3 were cultured in ...
Yinlong, Zhao, Shirui, Liu, Yu, Wen, Lili, Zhong   +3 more
openaire   +2 more sources

Modulation of the Biological Activity of microRNA‐210 with Peptide Nucleic Acids (PNAs)

ChemMedChem, 2011
AbstractHerein we describe the activity of a peptide nucleic acid (PNA) that targets microRNA‐210 (miR‐210), which is associated with hypoxia and is modulated during erythroid differentiation. PNAs directed against miR‐210 were designed to bind with high affinity to the target RNA strand and to undergo efficient uptake in target cells.
FABBRI, Enrica, Manicardi A, Tedeschi T, Sforza S, BIANCHI, Nicoletta, BROGNARA, Eleonora, FINOTTI, Alessia, BREVEGLIERI, Giulia, BORGATTI, Monica, Corradini R, Marchelli R, GAMBARI, Roberto   +11 more
openaire   +4 more sources

MicroRNA-210 overexpression predicts poorer prognosis in glioma patients

Journal of Clinical Neuroscience, 2014
MicroRNA-210 (miR-210) levels are elevated in many tumor types, are frequently associated with hypoxia induction, and are correlated with poor prognosis in many solid tumors. miR-210 regulates cell growth, angiogenesis, invasion, and apoptosis of many human tumors. In this study, we investigated the clinical significance of miR-210 expression in common
Nian-Sheng, Lai, Qing-Sheng, Dong, Hao, Ding, Zeng-Li, Miao, Yu-Chang, Lin   +4 more
exaly   +3 more sources

Serum microRNA-210 as a potential noninvasive biomarker for the diagnosis and prognosis of glioma [PDF]

British Journal of Cancer, 2015
MicroRNA-210 (miR-210) is an oncogenic miRNA previously associated with prognosis in human gliomas, an incurable tumour type of the central nervous system. Here miR-210 was investigated as a potential serum biomarker in the diagnosis and prognosis of glioma.Serum was immediately prepared from blood samples collected from patients with glioma grades I ...
Lai, N-s, Wu, D-g, Fang, X-g, Lin, Y-c, Chen, S-s, Li, Z-b, Xu, S-s   +6 more
exaly   +3 more sources

The expression and mechanism of action of MicroRNA-210 in preeclampsia

Clinical and Investigative Medicine
Background: MicroRNA-210 (miR-210) has been implicated in various diseases through its regulation of the Janus kinase–signal transducer and activator of transcription (JAK–STAT) signalling pathway. Despite this, its specific involvement in preeclampsia remains poorly understood.
Chunfeng Li, Yong Li, Lixia Wang, Nina Wang, Li Sun, Jing Wang   +5 more
openaire   +1 more source

MicroRNA-210 Mediates Hypoxic Pulmonary Hypertension in the Newborn Lamb

Hypertension
BACKGROUND: Pulmonary hypertension of the newborn is a life-threatening disorder characterized by elevated pulmonary vascular resistance due to maladaptation of the pulmonary circulation after birth. The pathogenesis and mechanisms underlying pulmonary hypertension of the newborn remain unclear, hindering the ...
Xiang-Qun Hu, Rui Song, Chiranjib Dasgupta, Stephen Twum-Barimah, Taiming Liu, Abu Ahmed, Shawn F. Hanson, Lubo Zhang, Arlin B. Blood   +8 more
openaire   +2 more sources