Results 131 to 140 of about 282,025 (323)
Advances in Nano‐Immunomodulatory Systems for the Treatment of Acute Kidney Injury
Advanced Science, EarlyView.Based on the biodegradability and the immunological reactiveness, IMNs can be broadly classified into four categories. The first category includes types of biologically derived materials that cause immunomodulatory action and biodegradability like nanoparticles of cell membranes, extracellular vesicles, and exosomes.
Chenli Zhang +5 more
wiley +1 more source
مجله انفورماتیک سلامت و زیست پزشکی, 2021 Introduction: The prediction of microRNAs related to target genes using bioinformatics tools saves time and costs of the experimental analyses. In the present study, the prediction of microRNA target genes relevant to Alzheimer’s Diseases (AD) were ...
Maryam Koraei, Shamseddin Ahmadi
doaj
Origins of Binary Gene Expression in Post-transcriptional Regulation by MicroRNAs [PDF]
Eur. Phys. J. E (2012) 35:102, 2012 MicroRNA-mediated regulation of gene expression is characterised by some distinctive features that set it apart from unregulated and transcription factor-regulated gene expression. Recently, a mathematical model has been proposed to describe the dynamics of post-transcriptional regulation by microRNAs. The model explains the observations made in single
arxiv
Advanced Science, EarlyView.This study verifies that circRNA‐mTOR exhibits high expression levels in HCC and has a strong correlation with patient prognosis. Mechanistically, circRNA‐mTOR achieves this effect by facilitating the nuclear translocation of RNA‐binding protein (RBP) PSIP1 through specific binding.
Yongchang Tang +12 more
wiley +1 more source
MicroRNAs: Something New Under the Sun [PDF]
, 2002 Eric G. Moss, R. Scott Poethig
openalex +1 more source
On the functional properties of microRNA-mediated feed forward loops [PDF]
arXiv, 2008 Motivation: Recent studies of genomic-scale regulatory networks suggested that a feed-forward loop (FFL) circuitry is a key component of many such networks. This led to a study of the functional properties of different FFL types, where the regulatory elements are transcription factors.
arxiv
Advanced Science, EarlyView.Comprehensive epigenomic and transcriptomic profiling revealed a dynamic enhancer landscape and gene expression program associated with nephrolithiasis, highlighting RXRα as a central transcription factor in this regulatory network. Tubular‐specific deletion of RXRα increased intrarenal CaOx crystal deposition, while its activation with Bexarotene ...
Yu Yang +12 more
wiley +1 more source
Oscillation in microRNA Feedback Loop [PDF]
arXiv, 2013 The dynamic behaviors of microRNA and mRNA under external stress are studied with biological experiments and mathematics models. In this study, we developed a mathematic model to describe the biological phenomenon and for the first time reported that, as responses to external stress, the expression levels of microRNA and mRNA sustained oscillation. And
arxiv
Advanced Science, EarlyView.In CLas‐infected D. citri, CLas lowers 20E levels initially, relieving the suppression of ETH release. The subsequent increase in ETH levels upregulates its receptor DcETHR and activates the JH signaling pathway. The signaling cascade of 20E‐ETH/ETHR‐JH along with miR‐210, targeting DcETHR, boost female fecundity in CLas+ D.
Xiaoge Nian +8 more
wiley +1 more source