Results 141 to 150 of about 285,352 (309)
Advanced Science, EarlyView.In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma +10 more
wiley +1 more source
microRNA-126 affects proliferation of undifferentiated thyroid carcinoma
, 2015 microRNA-126 affects proliferation of undifferentiated thyroid ...
A Salajegheh (19562203) +3 more
core
Die Bedeutung von microRNAs für die Funktion von Endothelzellen [PDF]
, 2009 Dicer and Drosha are the major enzymes involved in microRNA processing. Using siRNA targeting Dicer and Drosha, thereby downregulating a substantial number of microRNAs in EC, we demonstrate a crucial role of both enzymes in angiogenic processes ...
Bonauer, Angelika
core
Serum MicroRNA-21 as a Biomarker for Allergic Inflammatory Disease in Children
, 2016 MicroRNAs (miRs) have emerged as useful biomarkers for different disease states, including allergic inflammatory diseases such as asthma and eosinophilic esophagitis (EoE). Serum miRs are a possible non-invasive method for diagnosis of such diseases.
Sawyers, Cindy +7 more
core +1 more source
A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance
Advanced Science, EarlyView.Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng +12 more
wiley +1 more source
Advanced Science, EarlyView.ESCC‐derived exosomal circAP2B1 promotes tumor progression by reprogramming mitochondrial metabolism via the ESRRA/KPNA1/MFN2 axis to induce M2 polarization of macrophages. ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication.
Yiru Wang +5 more
wiley +1 more source
MicroRNA-8073: Tumor suppressor and potential therapeutic treatment - Fig 1
, 2018 Intracellular, extracellular (A) or exosomal (B) miR-8073 expression in 6x104colorectal cancer cell HCT116 and normal cell HCoEpic. In Fig 1B, exosomes that were extracted from the same amount of the cell cultured supernatant used in Fig 1A, were assayed
Aiko Takayama (6160544) +4 more
core +1 more source
Advanced Science, EarlyView.Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li +17 more
wiley +1 more source
microRNA-126 protects ECs from EndMT downstream of ERG and FLI1.
, 2018 (A) ChIP-seq profiles of ERG, FLI1, and indicated histone modifications (siControl vs siERG+siFLI1) around EGFL7/microRNA-126 loci in HUVECs. (B) Relative expression of microRNA-126-3p quantified by qPCR in HUVECs treated with siERG, siFLI1, or both for ...
Hiroyuki Aburatani (162634) +7 more
core +1 more source