Results 141 to 150 of about 282,025 (323)

Identification of the c‐Jun/H19/miR‐19/JNK1 cascade during hepatic stellate cell activation

Clinical and Translational Medicine, 2023
Ying Sun, Chunyu Liu, Xu Guo, Jiayu Zhao, Anqi Xiao, Kai Yin, Ming Liu, Xinlei Sun, Xi Chen, Minghui Liu   +9 more
doaj   +1 more source

MicroRNAs as Modulators of Tumor Metabolism, Microenvironment, and Immune Response in Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma, 2021
Laura Gramantieri,1 Catia Giovannini,2,3 Fabio Piscaglia,1,4 Francesca Fornari3,5 1Division of Internal Medicine, Hepatobiliary and Immunoallergic Diseases, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; 2Department of Experimental ...
Gramantieri L, Giovannini C, Piscaglia F, Fornari F   +3 more
doaj  

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

Advanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong, Pei Li, Yi Jiang, Zhihan Wang, Shihui Fu, Hebin Che, Meng Liu, Xiaojing Zhao, Chunlei Liu, Chenghui Zhao, Qin Zhong, Chongyou Rao, Siwei Wang, Suyuan Liu, Dayu Hu, Dongjin Wang, Juntao Gao, Kai Guo, Xinwang Liu, En Zhu, Kunlun He   +20 more
wiley   +1 more source

Predictive capacity of a miRNA panel in identifying teratoma in post‐chemotherapy consolidation surgeries

BJUI Compass, Volume 4, Issue 1, Page 81-87, January 2023., 2023
Abstract Objectives To investigate the utility of a novel serum miRNA biomarker panel to distinguish teratoma from nonmalignant necrotic/fibrotic tissues or nonviable tumours in patients with NSGCT undergoing post‐chemotherapy consolidation surgery.
Joseph A. Moore, Michael J. Lehner, Simone Anfossi, Saumil Datar, Rebecca S. Tidwell, Matthew Campbell, Amishi Y. Shah, John F. Ward, Jose A. Karam, Christopher G. Wood, Lois L. Pisters, George A. Calin, Shi‐Ming Tu   +12 more
wiley   +1 more source

Dysregulation of the miR‐16‐WWP1 signalling pathway leads to colorectal tumorigenesis

Clinical and Translational Medicine, 2022
Xiaorui Chen, Yi Zhao, Qing Zhu, Yanqing Liu, Yang Luo, Wei Cheng, Bohan Zhang, Kai Wang, Xiaohong Jiang, Rui Liu, Yanbo Wang, Zhen Zhou, Xi Chen   +12 more
doaj   +1 more source

Sperm‐Derived CircRNA‐1572 Regulates Embryogenesis and Zygotic Genome Activation by Targeting CCNB2 via Bta‐miR‐2478‐L‐2

Advanced Science, EarlyView.
Sperm‐derived circRNA‐1572 competitively binds to bta‐miR‐2478‐L‐2 through a “sponge” mechanism to regulate cyclin B2 (CCNB2) expression, thereby modulating the distribution of fibrous actin (F‐actin) in early pig embryos, ensuring proper chromosome segregation during mitosis, and facilitating normal embryo cleavage and zygotic genome activation.
Yanfang Wu, Yaochang Wei, Yuelin Li, Yiming Dou, YongQiang Yang, Hanghang Liu, Xiaoyan Wang, Zheng Wang, Jianmin Su, Yong Zhang, Yongsheng Wang   +10 more
wiley   +1 more source

Counting vertebrate microRNAs [PDF]

, 2003
Jonathan B Weitzman
openalex   +1 more source

Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration

Advanced Science, EarlyView.
The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan, Meiqian Wu, Chaonan Zhu, Hao Yu, Minh Duc Pham, Katharina Bottermann, Yijie Mao, Yue Wang, Mathias Langner, Mirko Peitzsch, Arka Provo Das, Silke Kauferstein, Jonathan Ward, Peter Mirtschink, Andreas Michael Zeiher, Stefanie Dimmeler, Jaya Krishnan   +16 more
wiley   +1 more source

The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism [PDF]

, 2003
Peizhang Xu, Stephanie Y. Vernooy, Ming Guo, Bruce A. Hay   +3 more
openalex   +1 more source

Lactobacillus johnsonii Generates Cyclo(pro‐trp) and Promotes Intestinal Ca2+ Absorption to Alleviate CKD–SHPT

Advanced Science, EarlyView.
The mechanism map of how L.johnsonii generates cyclo(pro‐trp) to alleviate CKD–SHPT by promoting the expression of CaSR and TRPV4 in IECs, enhancing Ca2+ absorption, and negatively feedback inhibiting iPTH secretion. Abstract Patients with chronic kidney disease (CKD) are at a high risk of developing secondary hyperparathyroidism (SHPT), which may ...
Xiong Zeng, Lihua Sun, Huichao Xie, Shenhai Gong, Caibao Lu, Zhongwei Xu, Haidi Guan, Ben Han, Wei Wang, Zhengmin Zhang, Jieying Zhou, Shuai Wang, Yihui Chen, Weidong Xiao   +13 more
wiley   +1 more source