Results 161 to 170 of about 661,223 (352)

Continuing analysis of microRNA origins [PDF]

, 2013
Justin T. Roberts, Elvera A Cooper, Connor J Favreau, J. Howell, Lee G Lane, James E. Mills, Derrick C Newman, Tabitha J Perry, Meaghan E Russell, Brittany M Wallace, Glen M. Borchert   +10 more
openalex   +1 more source

LncRNA THUMPD3‐AS1 Regulates Behavioral and Synaptic Structural Abnormalities in Schizophrenia via miR‐485‐5p and ARHGAP8

Advanced Science, EarlyView.
Schizophrenia (SCZ) is linked to synaptic structural deficits driven by dysregulated noncoding RNAs. Using the novel ceRNAxis pipeline, THUMPD3‐AS1/miR‐485‐5p/ARHGAP8 is identified as a key regulator of actin cytoskeletal remodeling through noncanonical RhoB/C‐ROCK2 signaling. Modulating this axis ameliorates SCZ‐like phenotypes in mice and aligns with
Xiaojuan Gong, Lingxi Chen, Xin Guo, Anna Jiang, Yayi He, Chunxia Yan, Liang Ma, Jiayang Gao, Jinyu Zhang, Bao Zhang   +9 more
wiley   +1 more source

The emerging research field of extracellular RNA: an editorial preface

ExRNA, 2019
Ke Zen, Chen-Yu Zhang
doaj   +1 more source

microRNAs in aged sperm confer psychiatric symptoms to offspring through causing the dysfunction of estradiol signaling in early embryos

Cell Discovery, 2022
Gaoli Liang, Xiaoju Zhu, Zixuan Zhang, Li Chen, Huijin Feng, Shoubin Zhan, Huanhuan Hu, Ranran Yu, Chen-Yu Zhang, Zhichun Feng, Bing Yao, Yanbo Wang, Xi Chen   +12 more
doaj   +1 more source

ERβ/circAHNAK Axis Inhibits USP10–FMR1 Deubiquitination to Prevent m⁶A‐Mediated ADAM17 Decay and Promote Angiogenesis in Clear Cell Renal Cell Carcinoma

Advanced Science, EarlyView.
In clear cell renal cell carcinoma, estrogen receptor β (ERβ) upregulates circAHNAK, which competitively binds USP10 to prevent FMR1 deubiquitination, leading to FMR1 degradation. Loss of FMR1 hinders m⁶A‐dependent decay of ADAM17 mRNA, resulting in ADAM17 accumulation in tumor exosomes and enhanced angiogenesis.
Chao Xu, Sujing Zhang, Yuepeng Liu, Jingwei Lv, Yilong Cao, Yao Chen, Hao Sun, Bowei Zhang, Shengtao Dai, Jiehan Li, Xiaoling Li, Bei Shi, Qingyun Sun, Meng Zhu, Junfei Gu   +14 more
wiley   +1 more source

MicroRNA profiling implicates the insulin-like growth factor pathway in bleomycin-induced pulmonary fibrosis in mice [PDF]

, 2013
Lisa Honeyman, Mark Bazett, Tomasz G. Tomko, Christina K. Haston   +3 more
openalex   +1 more source

Microvesicles and Microvesicle-Associated microRNAs Reflect Glioblastoma Regression: Microvesicle-Associated miR-625-5p Has Biomarker Potential [PDF]

, 2022
N Simiónescu, Miruna Nemecz, Anca Roxana Petrovici, Ioan Sebastian Nechifor, Razvan-Cristian Buga, Marius Gabriel Dabija, Lucian Eva, Adriana Georgescu   +7 more
openalex   +1 more source

Intrinsic MicroRNA‐10a Restricts Regulatory T Cell Suppressive Function and Intestinal Repair by Coordinating Transcriptional, Metabolic, and Epithelial Repair Pathways

Advanced Science, EarlyView.
This study identifies microRNA‐10a (miR‐10a) as a key brake on regulatory T cell (Treg) suppressive function and intestinal repair. By targeting Blimp‐1, Uqcrq, and amphiregulin, miR‐10a restrains transcriptional, metabolic, and epithelial programs essential for Treg activity.
Wenjing Yang, Tianming Yu, Hui Yang, Suxia Yao, Ruihua Ma, Elizabeth M Steinert, Karen M Ridge, Weiguo Cui, Navdeep S Chandel, Yingzi Cong   +9 more
wiley   +1 more source

A Panel of Serum MicroRNAs as Specific Biomarkers for Diagnosis of Compound- and Herb-Induced Liver Injury in Rats

, 2012
Yu‐Wen Su, Xi Chen, Zhenzhou Jiang, Tao Wang, Cheng Wang, Yun Zhang, Jing Wen, Mei Xue, Dan Zhu, Yue Zhang, Yijing Su, Tong-Yue Xing, Chen‐Yu Zhang, Luyong Zhang   +13 more
openalex   +2 more sources

Overexpression of long intergenic noncoding RNA LINC00312 inhibits the invasion and migration of thyroid cancer cells by down-regulating microRNA-197-3p [PDF]

, 2017
Kai Liu, Wen Huang, Danqing Yan, Qing Luo, Min Xiang   +4 more
openalex   +1 more source