Results 161 to 170 of about 497,158 (357)

Arabidopsis MicroRNAs [PDF]

Plant Physiology, 2008
openaire   +2 more sources

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Dysregulation of the miR‐16‐WWP1 signalling pathway leads to colorectal tumorigenesis

Clinical and Translational Medicine, 2022
Xiaorui Chen, Yi Zhao, Qing Zhu, Yanqing Liu, Yang Luo, Wei Cheng, Bohan Zhang, Kai Wang, Xiaohong Jiang, Rui Liu, Yanbo Wang, Zhen Zhou, Xi Chen   +12 more
doaj   +1 more source

Most \u3cem\u3eCaenorhabditis elegans\u3c/em\u3e MicroRNAs are Individually Not Essential for Development or Viability [PDF]

, 2007
MicroRNAs (miRNAs), a large class of short noncoding RNAs found in many plants and animals, often act to post-transcriptionally inhibit gene expression. We report the generation of deletion mutations in 87 miRNA genes in Caenorhabditis elegans, expanding
Abbott, Allison L., Alvarez-Saavedra, Ezequiel, Ambros, Victor R., Bartel, David P., Hellman, Andrew B., Horvitz, H. Robert, Lau, Nelson C., McGonagle, Shannon M., Miska, Eric A.   +8 more
core   +1 more source

Glioma stem cell specific microRNA-mRNA interaction network [PDF]

, 2014
Sheila K. Singh, Kelly Burrell, Sameer Agnihotri, SEYED RASOUL JALALI, Gelareh Zadeh   +4 more
openalex   +1 more source

Macrophage‐Targeted Magnesium Ion‐Nourisher for NLRP3 Inflammasome Inhibition to Enhance Liver Inflammatory Disease Treatment

Advanced Science, EarlyView.
This report describes a nano magnesium nourisher, named MgC@PS, capable of targeted Mg2⁺ delivery to macrophages, effectively suppressing The nuclear factor kappa B (NF‐κB) activation and mitigating NLRP3 inflammasome‐driven pyroptosis in liver inflammation.
Li Wang, Zhuo Yan, Sindhu Yalavarthi, Yusif Abdul‐Rashid, Kiki Parker, Kyle Nowlin, Ethan Li, Jordan Mack, Josephine Wei, Hunter Vu, Zhenquan Jia, Jianjun Wei, Jilong Wang, Kerui Wu   +13 more
wiley   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

The emerging research field of extracellular RNA: an editorial preface

ExRNA, 2019
Ke Zen, Chen-Yu Zhang
doaj   +1 more source

microRNAs in aged sperm confer psychiatric symptoms to offspring through causing the dysfunction of estradiol signaling in early embryos

Cell Discovery, 2022
Gaoli Liang, Xiaoju Zhu, Zixuan Zhang, Li Chen, Huijin Feng, Shoubin Zhan, Huanhuan Hu, Ranran Yu, Chen-Yu Zhang, Zhichun Feng, Bing Yao, Yanbo Wang, Xi Chen   +12 more
doaj   +1 more source

P5597Increased adipose tissue microRNA-133a gene expression in patients with coronary artery disease: the effect of body mass index [PDF]

, 2018
Maria Marketou, George Kochiadakis, Joanna Kontaraki, Evangelos Zacharis, E. M. Kanoupakis, Eleftherios M. Kallergis, Hercules E. Mavrakis, D. Lempidakis, K Fragiadakis, E Katsouli, Panos E. Vardas, F. Parthenakis   +11 more
openalex   +1 more source