Results 171 to 180 of about 300,285 (315)

MicroRNAs and peritoneal dialysis. [PDF]

J Bras Nefrol
Abensur H.
europepmc   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

MicroRNAs as Biomarkers of Brain Tumor

Cancer Management and Research
Wojciech Jelski,1 Barbara Mroczko1,2 1Department of Biochemical Diagnostics, Medical University, Bialystok, Poland; 2Department of Neurodegeneration Diagnostics, Medical University, Bialystok, PolandCorrespondence: Wojciech Jelski, Department of ...
Jelski W, Mroczko B
doaj  

Differential expression of mitomiRs in pancreatic islet cells associated with maternal protein restriction. [PDF]

Islets
Jacovetti C, Regazzi R.
europepmc   +1 more source

The promotional effect of microRNA-103a-3p in cervical cancer cells by regulating the ubiquitin ligase FBXW7 function

, 2022
Li Ren, Jinjin Yang, Xiyan Meng, Junjun Zhang, Yiran Zhang   +4 more
openalex   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

Network Analysis to Identify MicroRNAs Involved in Alzheimer's Disease and to Improve Drug Prioritization. [PDF]

Biomedicines
Reyna A, Panni S.
europepmc   +1 more source

Network analysis of microRNAs and their regulation in human ovarian cancer [PDF]

, 2011
Sebastian Schmeier, Ulf Schaefer, Magbubah Essack, Vladimir B. Bajić   +3 more
openalex   +1 more source

Improvement of lung ischemia–reperfusion injury by inhibition of microRNA‐155 via reductions in neuroinflammation and oxidative stress of vagal afferent nerve [PDF]

, 2020
Yan Zhou, Lianjie Zhang, Jingjing Guan, Xin Yin   +3 more
openalex   +1 more source

TGFβ1 Activates Lnc‐APUE to Promote Tumor Metastasis via the Alu Element‐Driven STAU1‐Mediated Decay of CDH1 mRNA

Advanced Science, EarlyView.
We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li, Jia‐Hui Huang, Jin‐E Yang, Yi‐Hang Li, Juan‐Zhen Hong, Ting‐Ting Wang, Ying‐Lei Chi, Meng‐Zhi Wu, Wei Wang, Ying Zhu, Shi‐Mei Zhuang   +10 more
wiley   +1 more source