Results 101 to 110 of about 197,028 (259)

Long‐Term Prognosis, Residual Recurrence Risk, and Postoperative Management After Pathological Complete Response in Rectal Cancer

Cancer Nexus, EarlyView.
This graphical abstract summarizes the post‐pCR clinical pathway in locally advanced rectal cancer. After neoadjuvant radiotherapy and systemic therapy followed by surgery, patients achieving pCR (ypT0N0) generally have durable disease control, although residual risks of local and distant recurrence remain. Risk assessment, guideline‐based surveillance,
Jia‐ang Wang, Yingjiang Ye, Zhidong Gao, Sen Hou   +3 more
wiley   +1 more source

Model‐based clinical pharmacology profiling of subcutaneous nivolumab in renal cell carcinoma: Bridging to alternative dosing regimens and indications

Clinical Pharmacology &Therapeutics, EarlyView.
A novel model‐informed drug development (MIDD) approach was employed to derive the coprimary endpoints (time‐averaged serum concentration over 28 days [Cavgd28] and minimum serum concentration at steady state [Cminss]) of the phase III CheckMate 67T study (NCT04810078).
Yue Zhao, Zheyi Hu, Elizabeth Gibson, Li Zhu, Heather Vezina, Anna G. Kondic   +5 more
wiley   +1 more source

ANALYSIS OF THE GENETIC DIVERSITY OF "LOVRAN MARRON" (Castanea sativa Mill.) USING MICROSATELLITE MARKERS [PDF]

, 2012
Maruni (maroni) su sorte europskog pitomog kestena (Castanea sativa Mill.) dobivene selekcijom, koje se od davnina uzgajaju radi proizvodnje krupnih i kvalitetnih plodova.
Marko Zebec, Zebec, Marko, Idžojtić, Marilena, Zlatko Šatović, Marilena Idžojtić, Igor Poljak, Zlatko Liber, Poljak, Igor, Šatović, Zlatko, Liber, Zlatko   +9 more
core   +1 more source

The genetics of non-conventional wine yeasts: current knowledge and future challenges

Frontiers in Microbiology, 2016
Saccharomyces cerevisiae is by far the most widely used yeast in oenology. However, during the last decade, several other yeasts species has been purposed for winemaking as they could positively impact wine quality. Some of these non-conventional yeasts (
Isabelle eMasneuf-Pomarede, Isabelle eMasneuf-Pomarede, Marina eBely, Philippe eMarullo, Philippe eMarullo, Warren eAlbertin, Warren eAlbertin   +6 more
doaj   +1 more source

Repetitive flanking sequences (ReFS): novel molecular markers from microsatellite families

, 2007
Although microsatellite markers have become exceedingly popular in molecular studies of wild organisms, their development in some taxonomic groups is challenging.
Gould, P., Freeland, Joanna R., Freeland, J. R., Anderson, Sarah J., Anderson, S. J., Gould, Phil, Gould, P. J. L.   +6 more
core   +1 more source

Genetic diversity and inbreeding in the Greek Skyros horse [PDF]

, 2008
Inbreeding and heterozygosity levels were calculated in a population of 77 horses of the endangered Skyros breed that had been raised since 1988 at an experimental farm. Twenty one horses were inbred with average inbreeding coefficient of 0.11 (+/-0.02).
Avdi, M., Banos, G.
core   +1 more source

Neurolathyrism in Sub‐Saharan Africa—Assessing the Neurotoxic Risks of Lathyrus sativus Amid Drought and Food Security Challenges

Food Safety and Health, EarlyView.
Representation of grass pea consumption in drought‐stricken sub‐Saharan Africa sustains nutrition, but excess β‐ODAP exposure due to multiple reasons triggers neurolathyrism, a progressive neurotoxic disorder. ABSTRACT Neurolathyrism is a progressive motor neuron disease due to the consumption of Lathyrus sativus (grass pea) over long periods.
Biruk Demisse Ayalew, Muhammad Umar, Pakeezah Tabasum, Maria Qadri, Talha Farooq, Eskeatnaf Yosef Getachew, Zemichael Getu Alemayehu, Eden Haile Hagos, Hailemariam Shimelis Gebeyehu, Hanna Tsehay Abebe, Nuradin Abdi Ali, David Chinaecherem Innocent, Temesgen Mamo Sharew   +12 more
wiley   +1 more source

Development of Polymorphic Microsatellite Markers for Phyllostachys edulis (Poaceae), an Important Bamboo Species in China

Applications in Plant Sciences, 2013
Premise of the study: Polymorphic microsatellite markers were developed for Phyllostachys edulis (Poaceae), an ecologically and economically important bamboo species in China, to evaluate the genetic diversity and population genetic structure of P ...
Wei-Xin Jiang, Wen-Ju Zhang, Yu-Long Ding   +2 more
doaj   +1 more source

A Computed Tomography Radiomics Approach for Assessing the T Cell‐Inflamed Gene Expression Profile in Hepatocellular Carcinoma and Its Association With Immunotherapy Response

Health Care Science, EarlyView.
The T cell‐inflamed gene expression profile (GEP) provides a biomarker for immunotherapy response across various cancers. We established a CT‐based radiomics model to predict the T cell‐inflamed GEP and immunotherapy response in hepatocellular carcinoma (HCC).
Mimi Tang, Kaiyu Sun, Dasheng Wu, Yujian Zou, Jian Zhou, Bin Li, Huanjing Hu, Zhenpeng Peng, Jifei Wang, Bingsheng Huang, Shi‐Ting Feng, Shuling Chen   +11 more
wiley   +1 more source

Leishmania donovani populations in Eastern Sudan: temporal structuring and a link between human and canine transmission. [PDF]

, 2014
BACKGROUND: Visceral leishmaniasis (VL), caused by the members of the Leishmania donovani complex, has been responsible for devastating VL epidemics in the Sudan.
Baleela, Rania, Kuhls, Katrin, Mauricio, Isabel L., Fitzpatrick, Sinead, Katrin Kuhls, Llewellyn, Martin S, Mauricio, Isabel L, Martin S Llewellyn, Miles, Michael A, Michael A Miles, Miles, Michael A., Rania Baleela, Sinead Fitzpatrick, Gabriele Schönian, Llewellyn, Martin S., Schönian, Gabriele, Isabel L Mauricio   +16 more
core   +1 more source