Results 121 to 130 of about 269,745 (308)

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

open access: yesInterdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu   +6 more
wiley   +1 more source

Soybean seed coat properties as determinants of natto and sprout quality

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Improving breeding efficiency for superior soybean (Glycine max (L.) Merr.) germplasm used in natto and sprouts requires understanding how seed coat properties relate to quality and functional traits. METHODS We measured seed weight, water uptake, and sprout length and thickness across various genotypes tested at different locations
Mehri Hadinezhad   +4 more
wiley   +1 more source

Determination of population structure and stock composition of chum salmon (Oncorhynchus keta) in Russia determined with microsatellites [PDF]

open access: yes, 2008
Variation at 14 microsatellite loci was examined in 34 chum salmon (Oncorhynchus keta) populations from Russia and evaluated for its use in the determination of population structure and stock composition in simulated mixed-stock fishery samples.
Beacham, Terry D.   +3 more
core  

Demographic and Clinical Characteristics of Early‐Onset Colorectal Cancer in Sweden and Finland: A Multicentre Retrospective Cohort Study Over Three Decades

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Colorectal cancer is the third most common cancer worldwide, and the proportion of individuals diagnosed under the age of 50 years, referred to as early‐onset colorectal cancer (EOCRC), is increasing. The aim of this study was to evaluate how the demographic and clinical features of EOCR in northern Sweden and Finland have changed over time ...
Melina Charalambidi   +11 more
wiley   +1 more source

Predicted genetic consequences of alternative population control strategies for North American plains bison in Yellowstone National Park

open access: yesThe Journal of Wildlife Management, EarlyView.
Management of bison in Yellowstone National Park under the available strategies that maintained ≥3,500 individuals (1:1 sex ratio), removed <40% of the population at a time and prioritized relatives for removal were predicted to maintain genetic variation at levels consistent with long‐term conservation (>95% of existing variation).
Shawna J. Zimmerman   +2 more
wiley   +1 more source

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri   +7 more
wiley   +1 more source

microsatellite

open access: yes
Citation: 'microsatellite' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10963 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
openaire   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Status of reintroduced American marten in the Manistee National Forest within Michigan’s Northern Lower Peninsula [PDF]

open access: yes, 2012
American martens (Martes americana) were extirpated from the Lower Peninsula of Michigan as a result of overharvest for fur and habitat loss in the early 1900s.
Watkins, Julie M.
core   +1 more source

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