Development and characterization of tri- and tetra-nucleotide polymorphic microsatellite markers for skipjack tuna (Katsuwonus pelamis) [PDF]
, 2012 Skipjack tuna (katsuwonus pelamis) (SJT) is the largest tuna fishery in all the major oceans around the world, and the largest marine fishery in Sri Lanka. Knowledge of genetic population structure and effective population size of SJT in the Indian Ocean
Chand, Vincent +2 more
core +2 more sources
PLoS ONE, 2020 Siberian wild rye (Elymus sibiricus L.), an allotetraploid species, is a potentially high-quality perennial forage crop native to temperate regions. We used fluorescently conjugated oligonucleotides, representing ten repetitive sequences, including 6 ...
Jihong Xie +4 more
doaj +1 more source
Clinical and mechanism research progress on short tandem repeat ⁃ related neuromuscular diseases
Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 Short tandem repeat (STR) is a component of the human genome, the number of repeats of STR is prone to change during DNA replication, and when it exceeds a certain threshold, it will lead to the occurrence of diseases, most of which involve the nervous ...
WAN Ya‑lan +4 more
doaj +1 more source
Microsatellite Expansion Diseases: Repeat Toxicity Found in Translation [PDF]
Neuron, 2017 Sellier et al. (2017) show that translation of expanded CGG repeats in fragile X-associated tremor/ataxia syndrome is initiated at an upstream ACG near-cognate start codon. The resulting polyglycine-containing protein, but not repeat RNA, is pathogenic by disrupting the nuclear lamina.
Fen-Biao, Gao, Joel D, Richter
openaire +2 more sources
BioTechniques, 2003 We developed a technique to improve the efficiency of producing TAA repeat microsatellite markers linked to interspecific conserved genes. Template DNA was prepared from cultures derived from single bacterial artificial chromosome (BAC) colonies using a ...
Geoffrey C. Waldbieser +2 more
doaj +1 more source
Genetic variants of the promoter of the heme oxygenase-1 gene and their influence on cardiovascular disease (The Ludwigshafen risk and cardiovascular health study) [PDF]
, 2009 Background Heme oxygenase-1 is an inducible cytoprotective enzyme which handles oxidative stress by generating anti-oxidant bilirubin and vasodilating carbon monoxide.
Lüblinghoff, Nicola +7 more
core +2 more sources
RNA biology of disease-associated microsatellite repeat expansions [PDF]
Acta Neuropathologica Communications, 2017 Microsatellites, or simple tandem repeat sequences, occur naturally in the human genome and have important roles in genome evolution and function. However, the expansion of microsatellites is associated with over two dozen neurological diseases. A common denominator among the majority of these disorders is the expression of expanded tandem repeat ...
Kushal J. Rohilla, Keith T. Gagnon
openaire +3 more sources
BMC Genomics, 2018 Background Even though microsatellite loci frequently have been isolated using recently developed next-generation sequencing (NGS) techniques, this task is still difficult because of the subsequent polymorphism screening requires a substantial amount of ...
Yun Xia +4 more
doaj +1 more source
Extended microsatellite analysis in microsatellite stable, MSH2 and MLH1 mutation-negative HNPCC patients: Genetic reclassification and correlation with clinical features [PDF]
, 2004 Background: Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant disorder predisposing to predominantly colorectal cancer (CRC) and endometrial cancer frequently due to germline mutations in DNA mismatch repair (MMR) genes, mainly ...
Baretton, G. +9 more
core +1 more source
Isolation and characterization of microsatellite loci from two inbreeding bark beetle species (Coccotrypes) [PDF]
, 2003 We developed 14 microsatellite markers in Coccotrypes carpophagus and 14 in C. dactyliperda. These loci will be used for studying genetic structure and the level of inbreeding in populations in the Canary Islands and Madeira.
Armour JAL +9 more
core +1 more source