Results 11 to 20 of about 28,799 (216)

Functionally relevant microsatellites in sugarcane unigenes

BMC Plant Biology, 2010
Background Unigene sequences constitute a rich source of functionally relevant microsatellites. The present study was undertaken to mine the microsatellites in the available unigene sequences of sugarcane for understanding their constitution in the ...
Singh Nagendra K, Srivastava Prem, Sharma Tilak R, Gaikwad Kishor, Pandit Awadhesh, Parida Swarup K, Mohapatra Trilochan   +6 more
doaj   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

Microsatellite distribution on sex chromosomes at different stages of heteromorphism and heterochromatinization in two lizard species (Squamata: Eublepharidae: Coleonyx elegans and Lacertidae: Eremias velox)

BMC Genetics, 2011
Background The accumulation of repetitive sequences such as microsatellites during the differentiation of sex chromosomes has not been studied in most squamate reptiles (lizards, amphisbaenians and snakes), a group which has a large diversity of sex ...
Kratochvíl Lukáš, Pokorná Martina, Kejnovský Eduard   +2 more
doaj   +1 more source

Isolation and identification of a new set of microsatellite loci from Ucides cordatus genome [PDF]

Archives of Biological Sciences, 2015
A new set of microsatellite loci (simple sequence repeats, SSRs) from the overexploited mangrove crab Ucides cordatus is described in this study. Microsatellite isolation used a highly simplified and inexpensive protocol based on (i) multiple ...
Araújo Erlane S., Britto Fábio B., Carvalho Adriana M.F., Orasmo Gleice R., Diniz Fábio M.   +4 more
doaj   +1 more source

Sequence determinants of human microsatellite variability

BMC Genomics, 2009
Background Microsatellite loci are frequently used in genomic studies of DNA sequence repeats and in population studies of genetic variability. To investigate the effect of sequence properties of microsatellites on their level of variability we have ...
Jakobsson Mattias, Sandefur Conner I, Pemberton Trevor J, Rosenberg Noah A   +3 more
doaj   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Analyses of carnivore microsatellites and their intimate association with tRNA-derived SINEs

BMC Genomics, 2006
Background The popularity of microsatellites has greatly increased in the last decade on account of their many applications. However, little is currently understood about the factors that influence their genesis and distribution among and within species ...
Bosch Montserrat, Domingo-Roura Xavier, Andrés Olga, López-Giráldez Francesc   +3 more
doaj   +1 more source

The accuracy, feasibility and challenges of sequencing short tandem repeats using next-generation sequencing platforms. [PDF]

PLoS ONE, 2014
To date we have little knowledge of how accurate next-generation sequencing (NGS) technologies are in sequencing repetitive sequences beyond known limitations to accurately sequence homopolymers.
Monika Zavodna, Andrew Bagshaw, Rudiger Brauning, Neil J Gemmell   +3 more
doaj   +1 more source

Molecular karyotyping of Siberian wild rye (Elymus sibiricus L.) with oligonucleotide fluorescence in situ hybridization (FISH) probes.

PLoS ONE, 2020
Siberian wild rye (Elymus sibiricus L.), an allotetraploid species, is a potentially high-quality perennial forage crop native to temperate regions. We used fluorescently conjugated oligonucleotides, representing ten repetitive sequences, including 6 ...
Jihong Xie, Yan Zhao, Linqing Yu, Ruijuan Liu, Quanwen Dou   +4 more
doaj   +1 more source

Clinical and mechanism research progress on short tandem repeat ⁃ related neuromuscular diseases

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
Short tandem repeat (STR) is a component of the human genome, the number of repeats of STR is prone to change during DNA replication, and when it exceeds a certain threshold, it will lead to the occurrence of diseases, most of which involve the nervous ...
WAN Ya‑lan, YU Jia‑xi, DENG Jian‑wen, HONG Dao‑jun, WANG Zhao‑xia   +4 more
doaj   +1 more source