Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou +13 more
wiley +1 more source
Abundant variation in microsatellites of the parasitic nematode Trichostrongylus tenuis and linkage to a tandem repeat [PDF]
An understanding of how genes move between and within populations of parasitic nematodes is important in combating the evolution and spread of anthelmintic resistance.
Dawson, D.A. +17 more
core +1 more source
Extended microsatellite analysis in microsatellite stable, MSH2 and MLH1 mutation-negative HNPCC patients: Genetic reclassification and correlation with clinical features [PDF]
Background: Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant disorder predisposing to predominantly colorectal cancer (CRC) and endometrial cancer frequently due to germline mutations in DNA mismatch repair (MMR) genes, mainly ...
Gross, M. +9 more
core +1 more source
Rapid isolation of DNA sequences flanking microsatellite repeats
Peter S N Rowe, F Francis, Francis F
exaly +4 more sources
Elevated Microsatellite Alterations at Selected Tetranucleotide repeats (EMAST) testing in colorectal cancer using the costeffective qiaxcel advanced platform [PDF]
Objective: Elevated Microsatellite Alterations at Selected Tetranucleotide repeats (EMAST) is a type of microsatellite instability occurring in about 60% of colorectal cancers (CRCs) and is associated with metastases and decreased patient survival ...
S. Mohammadpour +4 more
core +1 more source
Microsatellite instability at tetranucleotide repeats in skin and bladder cancer [PDF]
Recently, a novel form of MSI has been described that occurs only at tetranucleotide repeat markers. This has been termed elevated microsatellite instability at selected tetranucleotide repeats (EMAST). EMAST has been related to alterations of the p53 gene, and to the nature of the repeat sequence.
Hadi, Danaee +7 more
openaire +2 more sources
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä +18 more
wiley +1 more source
Cytogenetic characterisation and chromosomal mapping of microsatellite and telomeric repeats in two gecko species (Reptilia, Gekkonidae) from Thailand [PDF]
Weera Thongnetr +5 more
openalex +2 more sources
Early detection of infection is very important for efficient management of Mycosphaerella graminicola leaf blotch. To monitor and quantify the occurrence of this fungus during the growing season, a diagnostic method based on real-time PCR was developed ...
Bahkali, A.H. +9 more
core +1 more source
Alu Repeats: A Source for the Genesis of Primate Microsatellites
As a result of their abundance, relatively uniform distribution, and high degree of polymorphism, microsatellites and minisatellites have become valuable tools in genetic mapping, forensic identity testing, and population studies. In recent years, a number of microsatellite repeats have been found to be associated with Alu interspersed repeated DNA ...
S S, Arcot +4 more
openaire +2 more sources

