Results 31 to 40 of about 28,249 (264)

Microsatellite instability at tetranucleotide repeats in skin and bladder cancer [PDF]

Oncogene, 2002
Recently, a novel form of MSI has been described that occurs only at tetranucleotide repeat markers. This has been termed elevated microsatellite instability at selected tetranucleotide repeats (EMAST). EMAST has been related to alterations of the p53 gene, and to the nature of the repeat sequence.
Hadi, Danaee, Heather H, Nelson, Margaret R, Karagas, Alan R, Schned, Tara Devi S, Ashok, Tomoko, Hirao, Ann E, Perry, Karl T, Kelsey   +7 more
openaire   +2 more sources

Functional and immunological relevance of Anaplasma marginale major surface protein 1a sequence and structural analysis.

PLoS ONE, 2013
Bovine anaplasmosis is caused by cattle infection with the tick-borne bacterium, Anaplasma marginale. The major surface protein 1a (MSP1a) has been used as a genetic marker for identifying A.
Alejandro Cabezas-Cruz, Lygia M F Passos, Katarzyna Lis, Rachel Kenneil, James J Valdés, Joana Ferrolho, Miray Tonk, Anna E Pohl, Libor Grubhoffer, Erich Zweygarth, Varda Shkap, Mucio F B Ribeiro, Agustín Estrada-Peña, Katherine M Kocan, José de la Fuente   +14 more
doaj   +1 more source

Alu Repeats: A Source for the Genesis of Primate Microsatellites

Genomics, 1995
As a result of their abundance, relatively uniform distribution, and high degree of polymorphism, microsatellites and minisatellites have become valuable tools in genetic mapping, forensic identity testing, and population studies. In recent years, a number of microsatellite repeats have been found to be associated with Alu interspersed repeated DNA ...
S S, Arcot, Z, Wang, J L, Weber, P L, Deininger, M A, Batzer   +4 more
openaire   +2 more sources

APMicroDB: A microsatellite database of Acyrthosiphon pisum

Genomics Data, 2017
Pea aphids represent a complex genetic system that could be used for QTL analysis, genetic diversity and population genetics studies. Here, we described the development of first microsatellite repeat database of the pea aphid (APMicroDB), accessible at ...
Ritika Bishnoi, Deepak Singla
doaj   +1 more source

Analysis of microsatellite polymorphism in inbred knockout mice. [PDF]

PLoS ONE, 2012
Previously, we found that the genotype of 42 out of 198 mouse microsatellite loci, which are distributed among all chromosomes except the Y chromosome, changed from monomorphism to polymorphism (CMP) in a genetically modified inbred mouse strain. In this
Baofen Zuo, Xiaoyan Du, Jing Zhao, Huixin Yang, Chao Wang, Yanhua Wu, Jing Lu, Ying Wang, Zhenwen Chen   +8 more
doaj   +1 more source

Distribution and Comparative Analysis of Genomic Microsatellites in Nine Species of Family Sillaginidae

Fishes
We conducted a comparative analysis of the identified microsatellite sequences across the genomes of nine sillaginids. We examined the microsatellites with motifs ranging from 1 to 6 bp in length and analyzed their distribution and frequency across ...
Yinquan Qu, Caihui Qu, Changxu Tian, Tianxiang Gao, Yuan Zhang   +4 more
doaj   +1 more source

Microsatellite Markers for the New Zealand Endemic Tree Fuchsia excorticata (Onagraceae)

Applications in Plant Sciences, 2013
Premise of the study: Microsatellite markers were developed from a New Zealand endemic understory tree, Fuchsia excorticata, to investigate factors affecting the mating system.
Megan L. Van Etten, Alastair W. Robertson, Jennifer A. Tate   +2 more
doaj   +1 more source

Signatures of Population Expansion in Microsatellite Repeat Data

Genetics, 1998
Abstract To examine the signature of population expansion on genetic variability at microsatellite loci, we consider a population that evolves according to the time-continuous Moran model, with growing population size and mutations that follow a general asymmetric stepwise mutation model.
M, Kimmel, R, Chakraborty, J P, King, M, Bamshad, W S, Watkins, L B, Jorde   +5 more
openaire   +2 more sources

Microsatellite Expansion Diseases: Repeat Toxicity Found in Translation [PDF]

Neuron, 2017
Sellier et al. (2017) show that translation of expanded CGG repeats in fragile X-associated tremor/ataxia syndrome is initiated at an upstream ACG near-cognate start codon. The resulting polyglycine-containing protein, but not repeat RNA, is pathogenic by disrupting the nuclear lamina.
Fen-Biao, Gao, Joel D, Richter
openaire   +2 more sources

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source