Results 31 to 40 of about 197,824 (292)

Elevated Microsatellite Alterations at Selected Tetranucleotide repeats (EMAST) testing in colorectal cancer using the costeffective qiaxcel advanced platform [PDF]

, 2019
Objective: Elevated Microsatellite Alterations at Selected Tetranucleotide repeats (EMAST) is a type of microsatellite instability occurring in about 60% of colorectal cancers (CRCs) and is associated with metastases and decreased patient survival ...
S. Mohammadpour, M. Porhoseingholi, H. Goodarzi, M. Jafarinia, E. Nazemalhosseini-Mojarad   +4 more
core   +2 more sources

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Molecular karyotyping of Siberian wild rye (Elymus sibiricus L.) with oligonucleotide fluorescence in situ hybridization (FISH) probes.

PLoS ONE, 2020
Siberian wild rye (Elymus sibiricus L.), an allotetraploid species, is a potentially high-quality perennial forage crop native to temperate regions. We used fluorescently conjugated oligonucleotides, representing ten repetitive sequences, including 6 ...
Jihong Xie, Yan Zhao, Linqing Yu, Ruijuan Liu, Quanwen Dou   +4 more
doaj   +1 more source

The accuracy, feasibility and challenges of sequencing short tandem repeats using next-generation sequencing platforms. [PDF]

PLoS ONE, 2014
To date we have little knowledge of how accurate next-generation sequencing (NGS) technologies are in sequencing repetitive sequences beyond known limitations to accurately sequence homopolymers.
Monika Zavodna, Andrew Bagshaw, Rudiger Brauning, Neil J Gemmell   +3 more
doaj   +1 more source

Abundant variation in microsatellites of the parasitic nematode Trichostrongylus tenuis and linkage to a tandem repeat [PDF]

, 2006
An understanding of how genes move between and within populations of parasitic nematodes is important in combating the evolution and spread of anthelmintic resistance.
Dawson, D.A., Adam, Aileen, Adam, A., Buckland, R, Keller, L F, Johnson, P.C.D., Johnson, Paul C D, Dawson, Deborah A, Webster, L M I, Webster, L.M.I., Buckland, R., Keller, Lukas F, Johnson, P C D, Dawson, D A, Webster, Lucy M I, Keller, L.F., Adam, A, Buckland, Robert   +17 more
core   +1 more source

Clinical and mechanism research progress on short tandem repeat ⁃ related neuromuscular diseases

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
Short tandem repeat (STR) is a component of the human genome, the number of repeats of STR is prone to change during DNA replication, and when it exceeds a certain threshold, it will lead to the occurrence of diseases, most of which involve the nervous ...
WAN Ya‑lan, YU Jia‑xi, DENG Jian‑wen, HONG Dao‑jun, WANG Zhao‑xia   +4 more
doaj   +1 more source

Polymorphic microsatellite repeats are not conserved between Leishmania donovani and Leishmania major

, 2002
Thirteen sets of polymerase chain reaction (PCR) primers were designed to amplify microsatellite loci identified in the genome sequence of Leishmania major. Polymorphisms were detected in L. major at all loci.
H.A. Noyes, Kemp, Stephen J, Ashford, R.W., S. J. Kemp, Jamjoom, Manal, Kemp, S. J., Noyes, H. A., Jamjoom, M.B., R. W. Ashford, Bates, Paul, M. B. Jamjoom, Noyes, Harry A, P. A. Bates, Ashford, R W   +13 more
core   +5 more sources

Rapid development of gene-tagged microsatellite markers from bacterial artificial chromosome clones using anchored TAA repeat primers

BioTechniques, 2003
We developed a technique to improve the efficiency of producing TAA repeat microsatellite markers linked to interspecific conserved genes. Template DNA was prepared from cultures derived from single bacterial artificial chromosome (BAC) colonies using a ...
Geoffrey C. Waldbieser, Sylvie M.A. Quiniou, Attila Karsi   +2 more
doaj   +1 more source

ProRepeat: an integrated repository for studying amino acid tandem repeats in proteins [PDF]

, 2011
ProRepeat (http://prorepeat.bioinformatics.nl/) is an integrated curated repository and analysis platform for in-depth research on the biological characteristics of amino acid tandem repeats.
Harm Nijveen, Lin, K., Jack A. M. Leunissen, K. Lin, Audrey David, Luo, H., Ke Lin, A. David, David, A., H. Nijveen, H. Luo, Leunissen, J.A.M., Nijveen, H., Hong Luo, J. A. M. Leunissen   +14 more
core   +1 more source

Bovine proteins containing poly-glutamine repeats are often polymorphic and enriched for components of transcriptional regulatory complexes [PDF]

, 2010
peer-reviewedBackground: About forty human diseases are caused by repeat instability mutations. A distinct subset of these diseases is the result of extreme expansions of polymorphic trinucleotide repeats; typically CAG repeats encoding poly-glutamine ...
Herman Raadsma, Raadsma Herman, Lynn David J, Hobbs, Matthew, Whan Vicki, McWilliam, Sean, Lynn, David J, Tellam, Ross L, Barendse William, Tellam Ross L, Ross L Tellam, Vicki Whan, McWilliam Sean, Khatkar Mehar, Lutzow Ylva, David J Lynn, William Barendse, Ylva Lutzow, Whan, Vicki, Khatkar, Mehar, Raadsma, Herman, Tellam, Ross L., Ylva Strandberg Lutzow, Barendse, William, Lutzow, Ylva Strandberg, Sean McWilliam, Lynn, David J., Lutzow, Ylva S, Matthew Hobbs, Hobbs Matthew, Mehar Khatkar, Strandberg Lutzow, Ylva   +31 more
core   +1 more source