Results 1 to 10 of about 169 (168)

Simple sequence repeats in prokaryotic genomes [PDF]

open access: yesProceedings of the National Academy of Sciences, 2007
Simple sequence repeats (SSRs) in DNA sequences are composed of tandem iterations of short oligonucleotides and may have functional and/or structural properties that distinguish them from general DNA sequences. They are variable in length because of slip-strand mutations and may also affect local structure of the DNA molecule or ...
Jan, Mrázek   +2 more
openaire   +2 more sources

Optimization of sequence alignment for simple sequence repeat regions [PDF]

open access: yesBMC Research Notes, 2011
Microsatellites, or simple sequence repeats (SSRs), are tandemly repeated DNA sequences, including tandem copies of specific sequences no longer than six bases, that are distributed in the genome. SSR has been used as a molecular marker because it is easy to detect and is used in a range of applications, including genetic diversity, genome mapping, and
Ogbonnaya Francis C   +2 more
openaire   +3 more sources

MSDB: A Comprehensive Database of Simple Sequence Repeats [PDF]

open access: yesGenome Biology and Evolution, 2017
Microsatellites, also known as Simple Sequence Repeats (SSRs), are short tandem repeats of 1-6 nt motifs present in all genomes, particularly eukaryotes. Besides their usefulness as genome markers, SSRs have been shown to perform important regulatory functions, and variations in their length at coding regions are linked to several disorders in humans ...
Avvaru, Akshay Kumar   +3 more
openaire   +2 more sources

Simple sequence repeats in mycobacterial genomes

open access: yesJournal of Biosciences, 2007
Simple sequence repeats (SSRs) or microsatellites are the repetitive nucleotide sequences of motifs of length 1-6 bp. They are scattered throughout the genomes of all the known organisms ranging from viruses to eukaryotes. Microsatellites undergo mutations in the form of insertions and deletions (INDELS) of their repeat units with some bias towards ...
Vattipally B, Sreenu   +3 more
openaire   +2 more sources

Simple sequence repeats in Haemophilus influenzae

open access: yesInfection, Genetics and Evolution, 2009
Simple sequence repeat (SSRs) of DNA are subject to high rates of mutation and are important mediators of adaptation in Haemophilus influenzae. Previous studies of the Rd KW20 genome identified the primacy of tetranucleotide SSRs in mediating phase variation (the rapid reversible switching of gene expression) of surface exposed structures such as ...
Power, P   +6 more
openaire   +3 more sources

Simple sequence repeats in the Helicobacter pylori genome [PDF]

open access: yesMolecular Microbiology, 1998
We describe an integrated system for the analysis of DNA sequence motifs within complete bacterial genome sequences. This system is based around ACeDB, a genome database with an integrated graphical user interface; we identify and display motifs in the context of genetic, sequence and bibliographic data. Tomb et al.
Saunders, N.   +3 more
openaire   +4 more sources

Differential Distribution of Simple Sequence Repeats in Eukaryotic Genome Sequences [PDF]

open access: yesMolecular Biology and Evolution, 2001
Complete chromosome/genome sequences available from humans, Drosophila melanogaster, Caenorhabditis elegans, Arabidopsis thaliana, and Saccharomyces cerevisiae were analyzed for the occurrence of mono-, di-, tri-, and tetranucleotide repeats.
M V, Katti, P K, Ranjekar, V S, Gupta
openaire   +2 more sources

A Simple Sequence Repeat-Based Linkage Map of Barley [PDF]

open access: yesGenetics, 2000
Abstract A total of 568 new simple sequence repeat (SSR)-based markers for barley have been developed from a combination of database sequences and small insert genomic libraries enriched for a range of short simple sequence repeats. Analysis of the SSRs on 16 barley cultivars revealed variable levels of informativeness but no obvious ...
RAMSAY, L.   +15 more
openaire   +3 more sources

Simple Sequence Repeats for Genetic Studies of Alpaca

open access: yesAnimal Biotechnology, 2008
Trace sequences from the 2X alpaca genome sequencing effort were examined to identify simple sequence repeats (microsatellites) for genetic studies. A total of 6,685 repeat-containing sequences were downloaded from GenBank, processed, and assembled into contigs representing an estimated 4,278 distinct sequences.
K M, Reed, L D, Chaves
openaire   +2 more sources

The Cipher Code of Simple Sequence Repeats in “Vampire Pathogens” [PDF]

open access: yesScientific Reports, 2015
Abstract Blood inside mammals is a forbidden area for the majority of prokaryotic microbes; however, red blood cells tropism microbes, like “vampire pathogens” (VP), succeed in matching scarce nutrients and surviving strong immunity reactions. Here, we found VP of Mycoplasma
Zou, Geng   +8 more
openaire   +5 more sources

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