Results 311 to 320 of about 402,376 (385)

Metastatic potential of small posterior uveal melanomas

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the prevalence of aggressive traits in small posterior uveal melanomas (UM). Methods This retrospective, multicentre cohort study included 804 patients with small posterior UM (≤9 mm in largest basal diameter, ≤3 mm in thickness) from centres in the UK, Germany, and Sweden.
Gustav Stålhammar, Helen Kalirai, Sarah E. Coupland, Salvatore Grisanti, Svenja Rebecca Sonntag, Ayseguel Tura, Antonio Eleuteri, Rumana N. Hussain, Heinrich Heimann, Hannah Coudé Adam   +9 more
wiley   +1 more source

Predictive value of ¹⁸F-FDG PET/CT metabolic parameters for gastric cancer patients' microsatellite instability status. [PDF]

BMC Cancer
Liang B, Na Z, Wang K.
europepmc   +1 more source

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Analysis of Genetic Diversity and Race Genetic Structure of Major Horse Breeds in Xinjiang, China. [PDF]

Animals (Basel)
Hou L, Sulayman A, Zeng Y, Zhou L, Aimaier A, Kader A, Shi L.   +6 more
europepmc   +1 more source

Nationwide Real‐World Usage of Blood‐Based (Liquid) Biomarker Testing in Japan

Cancer Science, EarlyView.
This database analysis explores how liquid biopsy testing is integrated into clinical practice in Japan. ABSTRACT Despite the advances in precision oncology through biomarker testing, not all patients are able to benefit from treatment decisions guided by tissue‐based testing like comprehensive genomic profiling (CGP).
Yasushi Yatabe, Ryosuke Watanabe, Yuko Kotera, Shotaro Yasuoka, Daisuke Ennishi   +4 more
wiley   +1 more source

Lifetime expression of egg rejection behaviour in Eurasian magpies is associated with variation in a polymorphic genetic marker. [PDF]

Sci Rep
Molina-Morales M, Avilés JM, Precioso M, Martínez JG, Morales MM.   +4 more
europepmc   +1 more source

Counting the Invisible: New Tools to Estimate the Number of Contributors From Sequence‐Based Microsatellite Genotyping of Environmental DNA Samples

Molecular Ecology Resources, EarlyView.
Olivier Lepais, Ivan Paz‐Vinas
wiley   +1 more source

Impact of TP53, KRAS, and APC Mutations on Neoadjuvant Chemotherapy Outcomes in Locally Advanced Rectal Cancer

Cancer Science, EarlyView.
Genetic profiling of TP53, KRAS, and APC mutations reveals potential as predictors of neoadjuvant chemotherapy efficacy in locally advanced rectal cancer, aiding personalized treatment strategies to improve survival and reduce recurrence risks. ABSTRACT Despite recent advances in neoadjuvant strategies for locally advanced rectal cancer (LARC), optimal
Tomohiro Takeda, Tatsuya Shonaka, Mishie Tanino, Katsuro Enomoto, Shoichiro Mizukami, Masahide Otani, Mizuho Ohara, Chikayoshi Tani, Kimiharu Hasegawa, Takahiro Ishii, Ayumu Sugitani, Chiho Maeda, Yusuke Ono, Yuji Uno, Nobue Tamamura, Shin‐ichi Chiba, Yusuke Mizukami, Hideki Yokoo   +17 more
wiley   +1 more source

Evolution of microsatellite instability testing in a population-based cohort of patients with colorectal cancer in France in the years leading up to official recommendations. [PDF]

BMC Cancer
Wilson S, Guittet L, Gardy J, Alves A, Dupont B, Dejardin O, Bouvier V.   +6 more
europepmc   +1 more source