Results 341 to 350 of about 398,176 (385)
Some of the next articles are maybe not open access.
Microsatellites for ecologists: a practical guide to using and evaluating microsatellite markers
Ecology Letters, 2006AbstractRecent improvements in genetic analysis and genotyping methods have resulted in a rapid expansion of the power of molecular markers to address ecological questions. Microsatellites have emerged as the most popular and versatile marker type for ecological applications.
Kimberly A. Selkoe, Robert J. Toonen
openaire +4 more sources
Microsatellite instability in cancer of the proximal colon.
Science, 1993Colorectal tumor DNA was examined for somatic instability at (CA)n repeats on human chromosomes 5q, 15q, 17p, and 18q. Differences between tumor and normal DNA were detected in 25 of the 90 (28 percent) tumors examined.
S. Thibodeau, G. Bren, D. Schaid
semanticscholar +1 more source
Of Microbes and Microsatellites
Cancer Immunology Research, 2018Abstract A ubiquitous oral cavity microbe, Fusobacterium nucleatum, is increasingly being implicated in colorectal cancer pathogenesis. An article in this issue elucidates the differential association of F. nucleatum with tumor-infiltrating lymphocytes depending on microsatellite instability status.
Alan P. Venook, Chloe E. Atreya
openaire +2 more sources
Trends in Ecology & Evolution, 1993
Many evolutionary studies, particularly kinship studies, have been limited by the availability of segregating genetic marker loci. Microsatellites promise to alleviate these problems. Microsatellite loci are segments of DNA with very short sequence motifs repeated in tandem; their often numerous alleles differ in the number of these repeat units.
Colin R. Hughes +2 more
openaire +3 more sources
Many evolutionary studies, particularly kinship studies, have been limited by the availability of segregating genetic marker loci. Microsatellites promise to alleviate these problems. Microsatellite loci are segments of DNA with very short sequence motifs repeated in tandem; their often numerous alleles differ in the number of these repeat units.
Colin R. Hughes +2 more
openaire +3 more sources
Microsatellites for Microbiologists
2012Microsatellites are repeating sequences of 2-6base pairs of DNA. Currently, they are used as molecular markers in many organisms, specifically in genetic studies analyzing kinship and population structure. In addition, they can be used to study gene duplication and/or deletion.
Lucinda A. Scriven +3 more
openaire +4 more sources
A new bovine dinucleotide repeat microsatellite: microsatellite INRA 18
Animal Genetics, 1993An Anonymous clone containing a (TG)11 Microsatellites was isolated from a bovine genomic Sau3A size selected (approx.500pb) pGEM-4-Z library by hybridization to poly (dC-dT). Primers for polymerase chai reaction (PCR) were designed to amplify the region containing this microsatellite.
Moazami-Goudarzi, Katayoun +3 more
openaire +5 more sources
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability.
Science, 1995Transforming growth factor-beta (TGF-beta) is a potent inhibitor of epithelial cell growth. Human colon cancer cell lines with high rates of microsatellite instability were found to harbor mutations in the type II TGF-beta receptor (RII) gene. Eight such
S. Markowitz +12 more
semanticscholar +1 more source
Mutational Dynamics of Microsatellites
Molecular Biotechnology, 2009Microsatellites are a ubiquitous class of simple repetitive DNA sequences, which are widespread in both eukaryotic and prokaryotic genomes. The use of microsatellites as polymorphic DNA markers has considerably increased both in the number of studies and in the number of organisms, primarily for genetic mapping, studying genomic instability in cancer ...
Francisco Fuentes, Atul Bhargava
openaire +3 more sources
2013
Microsatellites have been utilized for decades for genotyping individuals in various types of research. Automated scoring of microsatellite loci has allowed for rapid interpretation of large datasets. Although the use of software produces an automated process to score or genotype samples, several sources of error have to be taken into account to ...
Flores-Renteria, Lluvia (R17984) +1 more
openaire +4 more sources
Microsatellites have been utilized for decades for genotyping individuals in various types of research. Automated scoring of microsatellite loci has allowed for rapid interpretation of large datasets. Although the use of software produces an automated process to score or genotype samples, several sources of error have to be taken into account to ...
Flores-Renteria, Lluvia (R17984) +1 more
openaire +4 more sources
Setting microsatellites free [PDF]
Nature Medicine, 1996 Altered microsatellite DNA in the blood of cancer patients may provide a novel method for tumor detection (pages 1033-1037).
openaire +2 more sources