Results 31 to 40 of about 113,313 (266)

Hundreds of SNPs versus dozens of SSRs: which dataset better characterizes natural clonal lineages in a self-fertilizing fish?

open access: yesFrontiers in Ecology and Evolution, 2014
For more than two decades, mitochondrial DNA sequences and simple sequence repeats (SSRs, or microsatellite loci) have served as gold standards in population genetics.
Felix eMesak   +3 more
doaj   +1 more source

Fungal Genomic Resources for Strain Identification and Diversity Analysis of 1900 Fungal Species

open access: yesJournal of Fungi, 2021
Identification and diversity analysis of fungi is greatly challenging. Though internal transcribed spacer (ITS), region-based DNA fingerprinting works as a “gold standard” for most of the fungal species group, it cannot differentiate between all the ...
Mir Asif Iquebal   +14 more
doaj   +1 more source

Population structure of chum salmon and selection on the markers collected for stock identification

open access: yesEcology and Evolution, 2021
Genetic stock identification (GSI) is a major management tool of Pacific salmon (Oncorhynchus Spp.) that has provided rich genetic baseline data of allozymes, microsatellites, and single‐nucleotide polymorphisms (SNPs) across the Pacific Rim.
Shuichi Kitada, Hirohisa Kishino
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Analysis of spatiotemporal evolution characteristics and recovery patterns of mangrove forests in China since 1978

open access: yesEcological Indicators
Mangrove ecosystems have garnered significant attention for their pivotal role in the global carbon cycle and their contributions to multiple UN Sustainable Development Goals.
Minduan Xu   +4 more
doaj   +1 more source

Аpplicability of microsatellite loci designed for cosmopolitan species for the investigation of endemic species: a case study of Silene sendtneri Boiss.

open access: yesGlasnik Šumarskog Fakulteta Univerziteta u Banjoj Luci, 2021
Silene sendtneri Boiss. (Caryophyllaceae) is the Dinaric endemic plant species with white, decorative and scented flowers. Previous studies on this endemic species were based on morphology and effects on seed germination after the treatment with ...
Jasna Hanjalić   +6 more
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Microsatellite instability in sarcomas [PDF]

open access: yesAnnals of Surgical Oncology, 1998
Microsatellite instability (MIN) has been studied in a variety of carcinomas and gynecologic sarcomas, but never in musculoskeletal sarcomas.We evaluated 16 skeletal and soft tissue sarcomas at nine genetic loci from chromosomal regions 1q, 5q, 7q, 12p, 13q, 17p, 19q, and two at 11p--all potential regions of interest regarding musculoskeletal sarcomas ...
S S, Martin   +4 more
openaire   +2 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

ScribbleCDNet: Change detection on high-resolution remote sensing imagery with scribble interaction

open access: yesInternational Journal of Applied Earth Observations and Geoinformation
Change detection on high-resolution remote sensing imagery using end-to-end deep learning methods has attracted considerable attention in recent years.
Zhipan Wang   +4 more
doaj   +1 more source

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