Results 41 to 50 of about 197,028 (259)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A Web-Based Prototype System for Deforestation Detection on High-Resolution Remote Sensing Imagery With Deep Learning

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Forests are the largest carbon storage and carbon sinks on land and are closely related to global climate change. Using remote sensing images to monitor global deforestation has become the mainstream method, mainly because of their long time-series ...
Zhipan Wang, Zewen Mo, Yinyu Liang, Zijun Yang, Xiang Liao, Zhongwu Wang, Qingling Zhang   +6 more
doaj   +1 more source

Disentangling Species Delineation and Guiding Conservation of Endangered Magnolias in Veracruz, Mexico

Plants, 2021
The Mexican state of Veracruz has suffered very high deforestation rates in the last few decades, and despite the establishment of protected areas and conservation projects, primary forest is now mainly persisting in mostly small, scattered, fragmented ...
Fabián Augusto Aldaba Núñez, Emily Veltjen, Esteban Manuel Martínez Salas, Marie-Stéphanie Samain   +3 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Hundreds of SNPs versus dozens of SSRs: which dataset better characterizes natural clonal lineages in a self-fertilizing fish?

Frontiers in Ecology and Evolution, 2014
For more than two decades, mitochondrial DNA sequences and simple sequence repeats (SSRs, or microsatellite loci) have served as gold standards in population genetics.
Felix eMesak, Andrey eTatarenkov, Ryan L Earley, John C. Avise   +3 more
doaj   +1 more source

Fungal Genomic Resources for Strain Identification and Diversity Analysis of 1900 Fungal Species

Journal of Fungi, 2021
Identification and diversity analysis of fungi is greatly challenging. Though internal transcribed spacer (ITS), region-based DNA fingerprinting works as a “gold standard” for most of the fungal species group, it cannot differentiate between all the ...
Mir Asif Iquebal, Sarika Jaiswal, Vineet Kumar Mishra, Rahul Singh Jasrotia, Ulavappa B. Angadi, Bhim Pratap Singh, Ajit Kumar Passari, Purbajyoti Deka, Ratna Prabha, Dhananjaya P. Singh, Vijai Kumar Gupta, Rukam Singh Tomar, Harinder Singh Oberoi, Anil Rai, Dinesh Kumar   +14 more
doaj   +1 more source

Profiling the dead: generating microsatellite data from fossil bones of extinct Megafauna — protocols, problems, and prospects [PDF]

, 2011
We present the first set of microsatellite markers developed exclusively for an extinct taxon. Microsatellite data have been analysed in thousands of genetic studies on extant species but the technology can be problematic when applied to low copy number (
Holdaway, R.N., Houston, J., Allentoft, M.E., Willerslev, E., Rasmussen, M., Gilbert, M.T.P, Spencer, P., Jacomb, C., Bunce, M., Oskam, C.L., Hale, M.L.   +10 more
core  

Microsatellite-tree

, 2018
Microsatellite dataset, R script and tree of 445 strains indicating the phylogenic position of 4CAR1 and T73 used for QTL mapping.
Matthias Eder (21135), Carole Camarasa (205193), Sylvie Dequin (205208), Jean-Luc Legras (202388), Claire Brice (4846552), Isabelle Sanchez (205197)   +5 more
core   +1 more source

A preliminary investigation of microsatellite-based genotyping in Trichomonas vaginalis. [PDF]

, 2011
The genetic epidemiology of Trichomonas vaginalis is poorly understood at present. The recent release of the organism's genome sequence opens the way to investigation of polymorphic markers allowing strain identification.
John P. Ackers, Prokopi, Marianna, Marianna Prokopi, Clark, C Graham, C. Graham Clark, Ackers, John P, Chatzitheodorou, Theodoros, Theodoros Chatzitheodorou   +7 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source