This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo+6 more
wiley +1 more source
Essentially Derived Varieties in Ornamentals [PDF]
The concept of Essentially derived varieties (EDVs) was introduced in the UPOV 1991 act to protect the interests of the breeder of the initial variety. When a variety is considered as an EDV, authorisation for commercial exploitation is needed from the ...
Vosman, B.
core +2 more sources
Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco+18 more
wiley +1 more source
Microsatellite markers in Spanish lime (Melicoccus bijugatus Jacq., Sapindaceae), a neglected Neotropical fruit crop [PDF]
Spanish lime (Melicoccus bijugatus Jacq.) is aNeotropical fruit tree cultivated, mainly, in orchards for self-consumption or local sale. The genus Melicoccus includes other nine species with edible fruits, some of these species are at risk of extinction.
Andueza-Noh, Ruben H.+5 more
core +1 more source
The primary challenge facing modern agriculture, including viticulture, is the impact of climate change. The scientific community recommends exploring and utilizing both inter-varietal and intra-varietal variability of local grapevines within each region.
Qiying Lin-Yang+4 more
doaj +1 more source
Comparison of PCR-RFLP and SSR chloroplast markers in study of genetic structure of beech (Fagus orientalis) populations in Hyrcanian forests [PDF]
Chloroplast (cp) DNA polymorphism was analyzed in 14 populations of beech (Fagus orientalis Lipsky) by PCR-RFLP and microsatellite (SSR) chloroplast markers.
Parvin Salehi Shanjani
doaj
Characterization of microsatellite markers in cassava based on microsatellite-AFLP technique [PDF]
We developed molecular markers for cassava based on the microsatellite-amplified fragment length polymorphism (M-AFLP) technique. Twenty primer pairs were developed and used for the analysis of 48 samples of Manihot species, consisting of M. esculenta (33), M. esculenta ssp flabellifolia (3), M. chlorosticta (3), M.
Kanokporn Triwitayakorn+4 more
openaire +2 more sources
Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility
This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam+5 more
wiley +1 more source
Molecular cytogenetic differentiation of paralogs of Hox paralogs in duplicated and re-diploidized genome of the North American paddlefish (Polyodon spathula). [PDF]
BackgroundAcipenseriformes is a basal lineage of ray-finned fishes and comprise 27 extant species of sturgeons and paddlefishes. They are characterized by several specific genomic features as broad ploidy variation, high chromosome numbers, presence of ...
Amemiya, Chris T+7 more
core +4 more sources
Premise of the study: This work aimed to develop microsatellite markers for Cratylia mollis as tools to assess its genetic diversity and structure and to evaluate their potential cross-amplification in related species.
M. Cristina López-Roberts+2 more
doaj +1 more source