Results 71 to 80 of about 109,422 (246)

Development of Polymorphic Microsatellite Markers for Phyllostachys edulis (Poaceae), an Important Bamboo Species in China

open access: yesApplications in Plant Sciences, 2013
Premise of the study: Polymorphic microsatellite markers were developed for Phyllostachys edulis (Poaceae), an ecologically and economically important bamboo species in China, to evaluate the genetic diversity and population genetic structure of P ...
Wei-Xin Jiang   +2 more
doaj   +1 more source

Molecular–clinical characteristics and treatment outcomes in 163 metastatic colorectal neuroendocrine carcinomas with a comparison to colorectal adenocarcinomas

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Colorectal neuroendocrine carcinoma (CR‐NEC) is a rare digestive neuroendocrine neoplasm that frequently exhibits an adenocarcinoma component. Nonetheless, the underlying biology of CR‐NEC remains poorly understood. This study examined molecular and clinical features and palliative chemotherapy outcomes of metastatic CR‐NEC, with comparison
Siren Morken   +20 more
wiley   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia   +4 more
wiley   +1 more source

Pedigree and marker information requirements to monitor genetic variability

open access: yesGenetics Selection Evolution, 2003
There are several measures available to describe the genetic variability of populations. The average inbreeding coefficient of a population based on pedigree information is a frequently chosen option.
Johann Sölkner, Roswitha Baumung
doaj   +1 more source

Detection of MSI signals from peripheral blood for monitoring response to immune checkpoint blockade therapy in patients with advanced microsatellite‐unstable gastrointestinal cancers: A pilot study

open access: yesInternational Journal of Cancer, EarlyView.
What's New? A substantial proportion of patients with microsatellite‐unstable gastrointestinal adenocarcinomas do not benefit from immunotherapy. This study demonstrates that microsatellite instability can be reliably detected in plasma‐derived extracellular vesicle DNA from patients with microsatellite‐unstable gastrointestinal cancers.
Aysel Ahadova   +16 more
wiley   +1 more source

Targeting Microbiome Metabolites: Reshaping Immunotherapy and Clinical Management Strategies for Colorectal Cancer

open access: yesiMetaMed, EarlyView.
The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang   +3 more
wiley   +1 more source

Life Stage‐Specific Genetic Diversity and Landscape Characteristics Collectively Influence Genetic Recovery in Pometia pinnata Population 生活史阶段特异的遗传多样性与景观特征对番龙眼种群遗传恢复的协同影响

open access: yesIntegrative Conservation, EarlyView.
Pometia pinnata demonstrated life‐stage‐specific genetic responses to landscape features, with asymmetric gene flow patterns and population recovery following historical bottlenecks, revealing complex topographic and demographic influences on forest genetic structure.
Madhuparna Chatterjee   +5 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

In Silico Retrieving of Opium Poppy (Papaver Somniferum L.) Microsatellites

open access: yesAgriculture, 2015
Repetitive tandem sequences were retrieved within nucleotide sequences of opium poppy (Papaver somniferum L.) genomic DNA available in the GenBank® database.
Masárová Veronika   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy