Results 121 to 130 of about 55,423 (289)

Microsatellite instability: A 2024 update

Cancer Science
AbstractDeficient mismatch repair (dMMR) results in microsatellite instability (MSI), a pronounced mutator phenotype. High‐frequency MSI (MSI‐H)/dMMR is gaining increasing interest as a biomarker for advanced cancer patients to determine their eligibility for immune checkpoint inhibitors (ICIs). Various methods based on next‐generation sequencing (NGS)
Hiroyuki Yamamoto, Yoshiyuki Watanabe, Hiroyuki Arai, Kumiko Umemoto, Keisuke Tateishi, Yu Sunakawa   +5 more
openaire   +2 more sources

Metabolic‐immune interactions in gastric cancer T cells: A single‐cell atlas for prognostic biomarker identification

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Metabolic alterations and immune dysfunction within the gastric tumor microenvironment critically drive gastric cancer (GC) progression and therapeutic resistance. Although single‐cell RNA sequencing (scRNA‐seq) has unveiled cellular heterogeneity in GC, the metabolic landscapes of tumor cells and their interplay with immune components remain ...
Junjun Liu, Rui Zhao, Guodong Yao, Zhao Liu, Runze Shi, Jingshu Geng, Guanying Liang, Kexin Chen   +7 more
wiley   +1 more source

Lynch Syndrome (HNPCC) and Microsatellite Instability [PDF]

, 2004
Asad Umar
openalex   +1 more source

The role of TMEM119 in gastric adenocarcinoma and its specific effects on immunity

Journal of International Medical Research
Objective To investigate the prognostic significance and immunological implication of transmembrane protein 119 (TMEM119) in stomach adenocarcinoma (STAD).
Yating Liu, Xin Yan, Caihao Qu, Futian Tang, Qian Wang, Yumin Li   +5 more
doaj   +1 more source

Microsatellite instability in myeloid leukemias [letter; comment] [PDF]

, 1994
Nicholas C.P. Cross, H Silly, JM Goldman
openalex   +1 more source

Microsatellite Instability-high Signet Ring Cell Carcinoma of the Colon Treated With Immunotherapy: Report of a Case [PDF]

, 2023
Kota Arima, Norio Uemura, Kengo Tsuneyoshi, Hiroshi Fujita, Hideyuki Kuroki, Shinichiro Uemura, Norihisa Hanada, Hideo Baba, Yoshihiro Komohara   +8 more
openalex   +1 more source

Natural History of Duodenal Adenoma: An 11‐year Follow‐up

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Early detection and treatment are essential to decrease the mortality rate of duodenal cancer (DC). However, the natural history of DC remains unclear. A 78‐year‐old woman underwent screening esophagogastroduodenoscopy (EGD) before surgery for advanced colon cancer.
Hikaru Kuribara, Naomi Kakushima, Hiroyuki Hisada, Yosuke Tsuji, Akihiko Ichida, Kiyoshi Hasegawa, Junichi Nawa, Tetsuo Ushiku, Mitsuhiro Fujishiro   +8 more
wiley   +1 more source

Delivering precision oncology in metastatic breast cancer: Clinical impact of comprehensive genomic profiling—The CATCH experience

International Journal of Cancer, Volume 158, Issue 6, Page 1675-1689, 15 March 2026.
What's new? CATCH is a prospective precision oncology registry trial that harnesses whole‐genome/exome‐ and RNA‐sequencing to enable actionable biomarker detection in metastatic breast cancer patients of any subtype. The data of the first 412 consecutive patients with completed follow‐up in this real‐world, single‐center patient cohort provide robust ...
Mario Hlevnjak, Sabine Heublein, Verena Thewes, Lukas Wagener, Constantin Pixberg, Carlo Fremd, Laura Michel, Christian Maurer, Lars Buschhorn, Nicola Dikow, Fangyoumin Feng, Stefan Fröhling, Christel Herold‐Mende, Steffen Hirsch, Chen Hong, Daniel Hübschmann, Lena Jassowicz, Polina Kozyulina, Katrin Pfütze, Richard F. Schlenk, Hans‐Peter Sinn, Katharina Smetanay, Christoph Springfeld, Albrecht Stenzinger, Celina Wagner, Stephan Wolf, Andreas Trumpp, Dirk Jäger, Oliver Zivanovic, Marc Zapatka, Andreas Schneeweiss, Peter Lichter   +31 more
wiley   +1 more source

Microsatellite instability in Japanese gastric cancer [PDF]

, 1995
Hideaki Nakashima, Hiroshi Inoue, Masaki Mori, Hiroaki Ueo, Masahito Ikeda, Tsuyoshi Akiyoshi   +5 more
openalex   +1 more source

Supplementary Figures 1-4 from Colorectal Cancers with Microsatellite Instability Display Unique miRNA Profiles

, 2023
Francesc Balaguer, Leticia Moreira, Juan José Lozano, Alexander Link, Georgina Ramírez, Yan Shen, Míriam Cuatrecasas, Mildred Arnold, Stephen J. Meltzer, Sapna Syngal, Elena M. Stoffel, Rodrigo Jover, Xavier Llor, Antoni Castells, C. Richard Boland, Meritxell Gironella, Ajay Goel   +16 more
openalex   +1 more source