Results 281 to 290 of about 124,795 (370)

Exceptional Response to Pembrolizumab Following Durvalumab Failure in a Patient With Microsatellite Instability-High Cholangiocarcinoma. [PDF]

Cureus
Sasaki A, Matsuda K, Okamoto R.
europepmc   +1 more source

PUF60‐Regulated Isoform Switching of MAZ Modulates Gastric Cancer Cell Migration

Cancer Medicine, Volume 14, Issue 11, June 2025.
ABSTRACT Background As an essential transcription factor, Myc‐associated zinc‐finger protein (MAZ) is frequently upregulated in many human tumors and is a well‐documented oncogene. However, we found high expression of MAZ was closely associated with good survival outcomes in patients with stomach adenocarcinoma (STAD), and the underlying mechanism ...
Dong Xing, Ting Zhao, Chenchen Mao, Zheng Han, Wanxia Cai, Teming Zhang, Dianfeng Mei, Wangkai Xie, Jiaye Yu, Zhonghan Wu, Zhiyuan Chen, Shiyu Feng, Xian Shen, Xiangyang Xue, Dan Xiang   +14 more
wiley   +1 more source

Incidence, Risk and Trends of Multiple Primary Cancers in Patients With Colorectal Cancer: Evidence From the South Australian Cancer Registry

Cancer Medicine, Volume 14, Issue 11, June 2025.
In this study, the risk and trends of multiple primary cancers were estimated using large state‐wide data collected over 35 years. The findings revealed a significantly higher risk of subsequent primary cancers, with an increasing trend over time. These results underscore the need for informed strategies to enhance and refine surveillance programmes ...
Mulugeta Melku, Oliver G. Best, Jean M. Winter, Lauren A. Thurgood, Muktar Ahmed, Ganessan Kichenadasse, Murthy Mittinty, Molla M. Wassie, Erin L. Symonds   +8 more
wiley   +1 more source

Microsatellite Instability in Primary and Metastatic Melanoma

Journal of Investigative Dermatology, 1997
RICHETTA, Antonio Giovanni, Vitaliano Silipo, CALVIERI, Stefano, FRATI, Luigi, OTTINI, LAURA, Alessandro Cama, Renato Mariani Costantini   +6 more
openaire   +5 more sources

Clinical Use of Comprehensive Genomic Profiling Tests in Intrahepatic Cholangiocarcinoma: A Single‐Center Retrospective Study

Liver International Communications, Volume 6, Issue 2, June 2025.
ABSTRACT The clinical utility of comprehensive genomic profiling (CGP) in intrahepatic cholangiocarcinoma (ICC) remains to be fully elucidated. This study analysed CGP test results and evaluated treatment outcomes with fibroblast growth factor receptor (FGFR) inhibitors in patients with ICC, aiming to assess their efficacy in cases with specific FGFR ...
Makiko Urabe, Takuo Yamai, Kenji Ikezawa, Kazuhiro Kozumi, Yugo Kai, Ryoji Takada, Kaori Mukai, Tasuku Nakabori, Hiroshi Wada, Naotoshi Sugimoto, Kazuyoshi Ohkawa   +10 more
wiley   +1 more source

More subtle microsatellite instability better predicts fluorouracil insensitivity in colorectal cancer patients. [PDF]

Sci Rep
Miyashita K, Shioi S, Kajitani T, Koi Y, Shimokawa M, Makiyama A, Oda S, Esaki T.   +7 more
europepmc   +1 more source

Platelet‐to‐Neutrophil Ratio: A Novel Prognostic Indicator for Anti‐PD‐1‐Based Therapy in Relapsed/Refractory Hodgkin Lymphoma and Solid Tumors

MedComm, Volume 6, Issue 6, June 2025.
Patients with relapsed/refractory cHL who had high pretreatment peripheral platelet‐to‐neutrophil ratio acquired increased complete response rate and longer progression‐free survival after anti‐PD‐1‐based therapy. Additionally, the prognostic value of platelet‐to‐neutrophil ratio was validated in other cohorts of patients with advanced solid tumors ...
Yuting Pan, Xin Zhang, Chunmeng Wang, Nannan Lu, Yang Liu, Yixin Chang, Xueting Qin, Weidong Han, Jing Nie   +8 more
wiley   +1 more source

Linking LEDGF/p75 Overexpression With Microsatellite Instability and KRAS Mutations: A Small-Scale Study in Colorectal Cancer. [PDF]

Cancer Control
Liedtke V, Wartmann T, Shi W, Kahlert UD.   +3 more
europepmc   +1 more source

Oxidative Stress in Antigen Processing and Presentation

MedComm – Oncology, Volume 4, Issue 2, June 2025.
Reactive oxygen species (ROS) play a crucial role in antigen processing and presentation, essential for linking innate and adaptive immunity. While balanced ROS levels promote immune function, excess ROS can disrupt antigen recognition, resulting in immune dysfunction.
Qinxia Chang, Yaying Zhang, Xiaojun Liu, Peng Miao, Wenbing Pu, Shanshan Liu, Jing Zhang, Yuan Tian, Guobo Shen, Na Xie   +9 more
wiley   +1 more source

Detecting microsatellite instability in cancer <i>via</i> multiplexed orthogonal gap-enhanced Raman tags. [PDF]

Chem Sci
Fu G, Li J, Zhang Q, Lv C, Zhang Z, Wang X, Wu R, Chen L.   +7 more
europepmc   +1 more source