Results 271 to 280 of about 62,250 (302)

Microsatellite instability in breast cancer

Annals of Surgical Oncology, 1997
Microsatellites are short repetitive nucleotide sequences that, through mutation, can undergo either expansion or contraction. This novel mutational mechanism known as microsatellite instability may play a role in carcinogenesis. We investigated the incidence of microsatellite instability in a series of primary breast carcinoma surgical specimens.Using
E B, Rush, J E, Calvano, K J, van Zee, A D, Zelenetz, P I, Borgen   +4 more
openaire   +2 more sources

Microsatellite instability: Advances in diagnosis

Cancer
The authors discuss current standard approaches to mismatch repair/microsatellite instability assessment, as well as emerging approaches, in the context of a new study from Thomas et al. on a novel machine learning approach, MIAmS.
Patrick M. Boland, Shridar Ganesan
openaire   +2 more sources

Microsatellite Instability in Hematologic Malignancies

Leukemia & Lymphoma, 1997
Malignant transformation in humans occurs via different mechanisms including the activation of oncogenes and/or loss of tumor suppressor genes. Recently, DNA mismatch repair defects manifest as genome wide microsatellite instability have been described as an additional mechanism of tumorgenesis in humans.
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[Microsatellite instability].

Nihon rinsho. Japanese journal of clinical medicine, 2012
Tamotsu, Sugai, Noriyuki, Uesugi, Wataru, Habano, Kazuyuki, Suzuki   +3 more
openaire   +3 more sources

PCR Analysis of Microsatellite Instability

2003
Microsatellites are simple, tandemly repeated DNA sequences which are abundantly distributed throughout the human genome, and because of their polymorphic nature have been widely utilized as genetic markers (1). They consist of a repeating unit of 1-5 base pairs, averaging 25-60 bases in length, and are commonly found in the form d(CA)n:d(GT)n (2).
openaire   +2 more sources

Microsatellite instability in melanoma

Melanoma Research, 1994
G J, Walker, J M, Palmer, M K, Walters, D J, Nancarrow, N K, Hayward   +4 more
openaire   +2 more sources

Microsatellite Instability

New England Journal of Medicine, 2003
openaire   +2 more sources

Pembrolizumab in microsatellite instability high or mismatch repair deficient cancers: updated analysis from the phase II KEYNOTE-158 study

Annals of Oncology, 2022
M Maio, Paolo A Ascierto, P A Cassier
exaly  

Microsatellite Instability in Pediatric Gliomas

American Journal of Clinical Pathology, 2021
openaire   +2 more sources

Microsatellite Instability

2004
Wolfgang Dietmaier, Arndt Hartmann
openaire   +2 more sources