Tumour invasiveness, the local and systemic environment and the basis of staging systems in colorectal cancer [PDF]
, 2017 background: The present study aimed to examine the relationship between tumour invasiveness (T stage), the local and systemic environment and cancer-specific survival (CSS) of patients with primary operable colorectal cancer.
A Chrysanthopoulou +47 more
core +1 more source
EPMA position paper in cancer:current overview and future perspectives [PDF]
, 2015 At present, a radical shift in cancer treatment is occurring in terms of predictive, preventive, and personalized medicine (PPPM). Individual patients will participate in more aspects of their healthcare.
Bubnov, Rostylav +7 more
core +5 more sources
Endometrial cancer and microsatellite instability status
Open Medicine, 2014 Microsatellite instability (MSI) is an important factor in the development of various cancers as an identifier of a defective DNA mismatch repair system.
Kanopiene Daiva +5 more
doaj +1 more source
Expression Analysis of Fibronectin Type III Domain-Containing (FNDC) Genes in Inflammatory Bowel Disease and Colorectal Cancer [PDF]
, 2019 Background. Fibronectin type III domain-containing (FNDC) proteins fulfill manifold functions in tissue development and regulation of cellular metabolism.
Adler, Andreas +12 more
core +2 more sources
Colorectal cancer carcinogenesis: a review of mechanisms
Cancer Biology & Medicine, 2016 Colorectal cancer (CRC) is the second most common cancer in women and the third most common in men globally. CRC arises from one or a combination of chromosomal instability, CpG island methylator phenotype, and microsatellite instability.
Kanwal Tariq, Kulsoom Ghias
doaj +1 more source
Introgressive Hybridization and the Evolution of Lake-Adapted Catostomid Fishes. [PDF]
, 2016 Hybridization has been identified as a significant factor in the evolution of plants as groups of interbreeding species retain their phenotypic integrity despite gene exchange among forms.
Carson, Evan W +5 more
core +2 more sources
BRIP-1 germline mutation and its role in colon cancer: presentation of two case reports and review of literature. [PDF]
, 2019 BackgroundHereditary colon cancer is characterized by the inheritance of an abnormal gene mutation which predisposes to malignancy. Recent advances in genomic medicine have identified mutations in "novel" genes as conferring an increased risk of ...
Ali, Mir +2 more
core
Gastroenterology Research and Practice, 2012 Background. In gastric carcinogenesis, changes of DNA methylation appear to be an early molecular event, and the genome-wide methylation state is closely correlated with the level of long interspersed nucleotide element-1 (LINE-1) methylation.
Jin Su Kim +9 more
doaj +1 more source
Microsatellite instability in transitional cell carcinoma of the urinary tract and its relationship to clinicopathological variables and smoking [PDF]
, 1996 Τοyoaki Uchida +5 more
openalex +2 more sources