Results 221 to 230 of about 197,824 (292)

Preimplantation Genetic Testing of Spinocerebellar Ataxia Type 2-Robust Tools for Direct and Indirect Detection of the ATXN2 CAG Repeat Expansion. [PDF]

Int J Mol Sci
Asherah N, Lian M, Tan AS, Taguchi R, Chua P, Liu S, Lee CG, Chong SS.   +7 more
europepmc   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, Volume 183, Issue 22, Page 6574-6606, November 2026.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

<i>KRAS</i> Mutations Worsen Overall Survival Rates in Black but not White American Patients With Colon Cancer. [PDF]

Gastro Hep Adv
Koi M, Ahmedyar S, Premkumar A, Aisu Y, Keku TO, Carethers JM.   +5 more
europepmc   +1 more source

Asymmetric Migration Shapes Genetic Structure of the Invasive Avian Vampire Fly (Philornis downsi) Across the Galápagos Islands

Molecular Ecology, Volume 35, Issue 21, November 2026.
ABSTRACT Biological invasions on islands provide a natural framework to study how dispersal and connectivity influence evolutionary and ecological processes. The avian nest parasitic fly, Philornis downsi—first recorded in Darwin's finch nests in 1997—causes high mortality in endemic land birds, yet its inter‐island and sex‐specific patterns of ...
Abbie C. Hay, Sonia Kleindorfer, Lauren K. Common, Sally Potter, Jennifer A. H. Koop, George E. Heimpel, Sarah A. Knutie, Birgit Fessl, Lorraine Pérez‐Beauchamp, Rachael Y. Dudaniec   +9 more
wiley   +1 more source

The complete sequence of chloroplast genome of an important medicinal plant, <i>Chamaemelum nobile</i> Linaeus 1785 (Asteraceae). [PDF]

Mitochondrial DNA B Resour
Yang J, Jia H, Zhang X, Hua Z, Li K, Ling C.   +5 more
europepmc   +1 more source

Functional memory of drought affects leaf chemical defenses and microbial interactions in aspen

New Phytologist, Volume 252, Issue 4, Page 1413-1431, November 2026.
Experimental design of the common garden study. Summary Drought is an important driver of tree mortality, but its long‐term impacts on trait expression remain poorly understood. Leaves are a key interface at which trees respond to abiotic stress, and foliar traits such as chemical defenses and microbial communities may play a role in determining post ...
Aubrey M. Hawks, Jaycie C. Fickle, Kelly L. Kerr, Dale L. Forrister, Allison M. Perkins, Efthymia Symeonidi, Madelyn Allen, Cannon Fehrenbach, Hsiao‐Nung Chen, Richard L. Lindroth, William R. L. Anderegg, Talia L. Karasov   +11 more
wiley   +1 more source

Genetic diversity and population structure of the Dermacentor nuttalli in Northern China inferred from microsatellite markers. [PDF]

Parasit Vectors
Li C, Liu M, Afzal S, Mukhtar MU, Sulaimon N, Shanawany EEE, Bold B, Bayasgalan C, Ma R, Wang S, Zhao J, Hu Z, Zhang B, Sheng Z, Liu L, Hu Z, Zhao Z, Li J, Luo F, Hu W, Feng X.   +20 more
europepmc   +1 more source

Novel Amino Acid Changes Increase Phosphoenolpyruvate Carboxylase Output in planta

Plant, Cell &Environment, Volume 49, Issue 11, Page 8306-8321, November 2026.
ABSTRACT Characterization of previously reported Arabidopsis mutants with increased aluminum (Al) resistance (alr) resulting from greater release of Al‐chelating malate identified three unique amino acid substitutions that each impacts PHOSPHOENOLPYRUVATE CARBOXYLASE 1, a key anaplerotic carbon fixation enzyme.
Jinrui Sheng, Kevin Frausto, Sarah Haesaerts, Taylor J. Meyer, Maruša Prolič‐Kalinšek, Seán E. O'Leary, Remy Loris, Paul B. Larsen   +7 more
wiley   +1 more source

Development of CypriSSR: a genome-wide, chromosome-level microsatellite database for multiple cyprinidae species. [PDF]

Database (Oxford)
Saini P, Iquebal MA, Jaiswal S, Angadi UB.   +3 more
europepmc   +1 more source

The Relevance of Curative‐Intent Metastasectomy in Colorectal Cancer Patients: Real‐World Insights From a Certified Comprehensive Cancer Center in Germany

International Journal of Cancer, Volume 159, Issue 8, Page 2025-2035, 15 October 2026.
Patients with metastatic colorectal cancer who are ineligible for upfront metastasectomy may still become candidates for secondary metastasectomy with curative intent following response to primary chemotherapy. However, most studies dichotomize metastatic colorectal cancer into resectable and unresectable disease.
Julian W. Holch, Jo‐Ann Eisenburger, Antony Weber, Iris Kammermeier‐Wehlau, Yannick Wiberg, Fabian Allmendinger, Kathrin Heinrich, Lena Weiss, C. Benedikt Westphalen, Victoria Krenmayr, Klara Dorman, Danmei Zhang, Theres Fey, Karin Berger‐Thürmel, Ulrich Wirth, Florian Kühn, Michael von Bergwelt‐Baildon, Jens Werner, Volker Heinemann   +18 more
wiley   +1 more source