Results 291 to 300 of about 57,676 (330)

Analysis of Aspergillus spp. Isolates According to Temporal-Spatial, Sociodemographic, and Clinical Variables-Microsatellite Typing of Clinical and Environmental Samples of Aspergillus fumigatus in a University Hospital in Sao Paulo, Brazil. [PDF]

open access: yesMycoses
Fonseca CA   +18 more
europepmc   +1 more source

Safety and Efficacy Findings From a Phase Ib/II Study of ASP‐1929 Photoimmunotherapy With Pembrolizumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

open access: yesHead &Neck, Volume 48, Issue 1, Page 160-174, January 2026.
ABSTRACT Background ASP‐1929 photoimmunotherapy—cetuximab conjugated to IRDye 700DX and red light (690 nm) for localized drug activation—results in rapid, selective cell killing. Methods This phase Ib/II open‐label study evaluated ASP‐1929 photoimmunotherapy plus pembrolizumab in patients with recurrent/metastatic HNSCC (≥ 1 accessible lesion, PD‐L1 ...
David M. Cognetti   +17 more
wiley   +1 more source

Genetic differences between primary colorectal cancer and its paired synchronous and metachronous metastases

open access: yesInternational Journal of Cancer, Volume 158, Issue 1, Page 120-130, 1 January 2026.
What's new? Colorectal cancer (CRC) frequently metastasizes to the liver, either synchronously with primary diagnosis or metachronously, after variable time intervals. Although implicated, the role of genetic factors in driving synchronous and metachronous disease progression remains uncertain.
Marie Rajtmajerova   +16 more
wiley   +1 more source

Beyond PD‐1/PD‐L1: New Immune Checkpoints and Therapeutic Combinations in Cancer Immunotherapy

open access: yesMedicine Bulletin, Volume 2, Issue 1, Page 61-93, January 2026.
ABSTRACT Recently, immune checkpoint inhibitors (ICIs), particularly PD‐1/PD‐L1 and CTLA‐4 inhibitors, have revolutionized cancer treatment, significantly improving survival rates for various malignancies. However, ICI therapies targeting single checkpoints on T cells still face numerous challenges, such as low response rates and post‐treatment ...
Yangyang Li, Zizhen Kang, Yanyun Du
wiley   +1 more source

Preliminary genetic barcodes for ash (Fraxinus) species and generation of new wide hybrids

open access: yesPLANTS, PEOPLE, PLANET, Volume 8, Issue 1, Page 245-258, January 2026.
Societal Impact Statement The world‐wide diversity of ash trees includes genetic information encoding resistance to the ash dieback fungus and the emerald ash borer beetle, which are currently devastating ash populations in Europe and North America. In order to mobilise this genetic diversity in conventional breeding programmes, we need to be able to ...
William J. Plumb   +11 more
wiley   +1 more source

Microsatellite Instability and BAT-26 Marker Expression in a Mexican Prostate Cancer Population with Different Gleason Scores. [PDF]

open access: yesDiseases
Flores-Islas AK   +9 more
europepmc   +1 more source

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