Results 91 to 100 of about 2,794,950 (328)
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
SPATIAL REPARTITION OF CURRENT FLUCTUATIONS IN A SCANNING TUNNELING MICROSCOPE
Image Analysis and Stereology, 2011 Scanning Tunneling Microscopy (STM) is a technique where the surface topography of a conducting sample is probed by a scanning metallic tip. The tip-to-surface distance is controlled by monitoring the electronic tunneling current between the two metals ...
Jerome Lagoute +3 more
doaj +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
„Ludzkie owady” i człowiek – o dalekiej bliskości życia w niedoli i wspaniałości
Zoophilologica, 2016 The author analyzes E.T.A. Hoffmann’s short story Master Flea, focusing mainly on the scene of the telescope duel between two biologists: Jan Swammerdam and Anton Leeuwenhoek. This scene triggers reflection on discovering the closeness between humans and
Ireneusz Gielata
doaj
Criminocorpus, 2017 During the interwar period, men from Lyon’s police laboratory developed new microscopes in order to more efficiently fight crime. Graphoscope, hastoscope and synchrisiscope evolved at the climax of the structure Edmond Locard created in 1910.
Amos Frappa
doaj +1 more source
Attachment converts microscope to point source autocollimator [PDF]
, 1964 A low-power microscope or telescope provides a simple means of autocollimation. This is done by fitting the instrument with a light source to permit alignment from a reflecting surface normal to the optic axis of the ...
Shlichta, P. J.
core +1 more source
Status of MICROSCOPE, a mission to test the Equivalence Principle in space
, 2014 MICROSCOPE is a French Space Agency mission that aims to test the Weak Equivalence Principle in space down to an accuracy of $10^{-15}$. This is two orders of magnitude better than the current constraints, which will allow us to test General Relativity ...
Bergé, Joel +2 more
core +2 more sources
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
A Scanning Electron Microscope for Ultracold Atoms
, 2006 We propose a new technique for the detection of single atoms in ultracold quantum gases. The technique is based on scanning electron microscopy and employs the electron impact ionization of trapped atoms with a focussed electron probe.
+7 more
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Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source