Results 81 to 90 of about 2,794,950 (328)
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
, 2000 We describe the use of a near-field scanning microwave microscope to image the permittivity and tunability of bulk and thin film dielectric samples on a length scale of about 1 micron. The microscope is sensitive to the linear permittivity, as well as to
A. Stanishevsky +8 more
core +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Three-dimentional imaging in ultrasonic microscopy
Archives of Acoustics, 2014 Advances in modern technology increases requirements for nondestructive characterization of material and biological properties in the μm range. The acoustic microscope presented in this paper combines C-scan and B-scan modes. The data collected during
Krzysztof Dynowski +2 more
doaj
Minimal invasive endoscopic neurosurgery
Journal of Society of Surgeons of Nepal, 2016 Introduction and Objective: If microscope heralded a new era in delicate and precise neurosurgical procedures, endoscope introduced an element of minimal invasiveness and supplemented microscope where they could not reach.
Amit Thapa, Bidur KC, Bikram Shakya
doaj +1 more source
The detection of fimbriae by Transmission electron microscope in Salmonella isolated locally from patient in Kirkuk city and compared with some standard isolates . [PDF]
Kirkuk Journal of Science, 2009 This study include the detection of fimbriae by Transmission electron microscope in three type of locall isolates of Salmonella (S.typhi , S.typhimurium, S.montevideo) and compared with their standard strains (S.typhi , S.paratyphi B , S.
Dr.Hager Ali Shareef
doaj +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Scanning microSQUID Force Microscope
, 2001 A novel scanning probe technique is presented: Scanning microSQUID Force microscopy (SSFM). The instrument features independent topographic and magnetic imaging. The SSFM operates in a dilution refrigerator in cryogenic vacuum.
Hasselbach, K., Mailly, D., Veauvy, C.
core +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source