Results 121 to 130 of about 1,751,921 (298)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The Incidence of Microscopic Colitis: Microscopic No More [PDF]

Digestive Diseases and Sciences, 2017
Nicole M, Gentile, Eugene F, Yen
openaire   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Corrigendum: Asymptomatic Malaria Infection Is Maintained by a Balanced Pro- and Anti-inflammatory Response

Frontiers in Microbiology, 2021
Augustina Frimpong, Augustina Frimpong, Augustina Frimpong, Jones Amponsah, Abigail Sena Adjokatseh, Dorothy Agyemang, Lutterodt Bentum-Ennin, Ebenezer Addo Ofori, Ebenezer Addo Ofori, Eric Kyei-Baafour, Kwadwo Akyea-Mensah, Bright Adu, Gloria Ivy Mensah, Linda Eva Amoah, Linda Eva Amoah, Kwadwo Asamoah Kusi, Kwadwo Asamoah Kusi, Kwadwo Asamoah Kusi   +17 more
doaj   +1 more source

A comparison of microscopic traffic flow simulation systems for an urban area [PDF]

Transport Problems, 2010
The paper compares the results of an application of three selected systems (TRANSIMS, SUMO, and VISSIM) to the microscopic simulation of traffic flow for a fragment of a real urban road network.
Michał MACIEJEWSKI
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Wettability of the Plant Growth Regulator 28-HB on Pepper Leaves at Different Developmental Stages

Horticulturae
Studying the wettability of plant growth regulators on crop leaf surfaces is essential for enhancing crop yield. In this study, the wetting behavior of the plant growth regulator 28-homo-brassinolide (28-HB), supplemented with different surfactants, was ...
Xiaoya Dong, Kaiyuan Wang, Zhouming Gao, Cuicui Zhu, Xianping Guan, Baijing Qiu   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Research progress and prospects of surfactant flooding in molecular dynamics simulation

Youqi dizhi yu caishoulu
Surfactants are widely used in the tertiary recovery of oilfields， and it is of great significance to study the mechanism of surfactant flooding from the microscopic point of view.
LIU Feng, HAN Chunshuo, YU Linjun, ZHANG Yi, LIU Yancheng, GAO Xiaoquan, YANG Kai   +6 more
doaj   +1 more source