Results 171 to 180 of about 22,635 (241)

Piezo1‐mediated unfolded protein response in goblet cells regulates intestinal mucus barrier homeostasis through the Ca2+–IRE1α–XBP1 pathway

Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.
This study demonstrates that activation of Piezo1 channels in goblet cells by intestinal mechanical stimulation modulates ER calcium homeostasis via calcium ion (Ca2+) flux, which in turn regulates Mucin2 production and synthesis through the IRE1α‐XBP1. Intraperitoneal administration of Yoda1 alleviates mucus barrier impairment in DSS/WAS‐treated mice.
Jiandi Wu, Shaotong Wang, Zhe Wang, Jianhua Fang, Xueyan Li, Qingqing Zhang, Yan Dai, Wenjing Tian, Yize Ma, Gangping Li, Lei Zhang, Yudong Jiang, Xiaohua Hou, Jun Song   +13 more
wiley   +1 more source

Increased Colonic Levels of CD8+ Cytotoxic T lymphocyte-Associated Mediators in Patients With Microscopic Colitis. [PDF]

Inflamm Bowel Dis
Lushnikova A, Wickbom A, Bohr J, Kruse R, Wirén A, Hultgren Hörnquist E.   +5 more
europepmc   +1 more source

Persisting Region‐Specific Microglia Activation and Synaptic Imbalance During Remission in a DSS‐Induced Colitis Model

Glia, Volume 74, Issue 11, November 2026.
Relapsing colitis region‐specific microglial states beyond remission. Cortical microglia remain pro‐inflammatory and synapse‐disruptive, while hippocampal microglia shift toward a reparative program that maintains neuronal circuit stability. ABSTRACT Ulcerative colitis (UC) patients experience cycles of active gut inflammation and remission, with ...
Lorena Morton, Luis E. Villafuerte, Alejandra P. Garza, Nina Lindemann, Elisa Wider‐Eberspächer, Dunja Bruder, Ildiko R. Dunay   +6 more
wiley   +1 more source

Manifestations of the oral mucosa and salivary glands in irritable bowel syndrome and microscopic colitis - A systematic review. [PDF]

Acta Odontol Scand
Göthlin H, Hasséus B, Sjöberg K, Bankvall M.   +3 more
europepmc   +1 more source

Colonic Barrier Dysfunction and Inflammation Induced by Nano‐/Micro‐Plastics Fibers in Mice via the FAK/NF‐κB/iNOS and TLR4/NF‐κB/iNOS Pathways

Journal of Applied Toxicology, Volume 46, Issue 11, Page 4144-4159, November 2026.
ABSTRACT As emerging environmental contaminants, nano‐ and micro‐plastics (NMPs) have drawn increasing research attention due to potential hazards to organisms. Particle shape is a key factor influencing the toxic effects of NMPs, and NMPs of different shapes cause varying degrees of tissue damage. We investigated the specific mechanisms of polystyrene
Yuting Li, Shibo Bao, Puyang Huang, Jiahui Wang, Hongfeng Li, Yahong Liu, Kai Wang, Jianjun Du, Lingjun Yan, Guowei Pan, Wei Sun   +10 more
wiley   +1 more source

Vonoprazan-associated Microscopic Colitis and Continued Use After Onset: A Study Using a Japanese Pharmacovigilance Database. [PDF]

In Vivo
Nakanishi K, Uwai Y, Nabekura T.
europepmc   +1 more source

A Case of Disseminated Encephalitozoon cuniculi in a Lung Transplant Recipient: Microsporidiosis in the Era of Molecular Diagnostics

Transplant Infectious Disease, EarlyView.
Lee S. Gottesdiener, Clare DeLaurentis, Marcus R. Pereira   +2 more
wiley   +1 more source

Feasibility of a Multimodal Lifestyle Intervention Programme for Patients With Ulcerative Colitis: A Single‐Arm Pilot Study

JCC Plus, Volume 1, Issue 6, November 2026.
ABSTRACT Introduction Although individual lifestyle interventions have shown promise in improving well‐being in patients with ulcerative colitis (UC), the feasibility of a multimodal approach remains unclear. This study assessed the feasibility of a multimodal lifestyle intervention programme.
Dorien Oomkens, Willemijn van Dop, Mirjam Severs, Suzanne Kooij, Rianne Vehof, Floor Bennebroek Evertsz, Baukje van den Heuvel, Marjolijn Duijvestein   +7 more
wiley   +1 more source

Autoimmune Thyroid Diseases and Microscopic Colitis: A Nationwide Matched Case-Control Study in Sweden.

J Clin Endocrinol Metab
Bergman D, Kang X, Sun J, Ebrahimi F, Ludvigsson JF.   +4 more
europepmc   +1 more source

Coeliac Disease, Microscopic Colitis, and Exclusion Diets-A Commemorative Issue in Honor of Dr. Fernando Fernández-Bañares. [PDF]

Nutrients
Esteve M, Arau B, Martín-Cardona A.
europepmc   +1 more source