Results 151 to 160 of about 277,529 (354)

Digital Image Analysis of Actinomycetes Colonies as a Potential Aid for Rapid Taxonomic Identification

open access: yes, 2010
High frequency isolation of actinomycetes poses a challenge for the taxonomists hence simple and rapid identification methods are required. Our work to catalogue biodiversity of actinomycetes of Goa yielded several distinct morphotypes.
Sonashia Velho-Pereira   +1 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Variation of illumination in DF microscopic images due to the density of different cells in the image.

open access: yes, 2018
Variation of illumination in DF microscopic images due to the density of different cells in the image.
Rares Buiga (6083135)   +3 more
core   +1 more source

Performance Comparison of Urine Sediment Analytical Tool by Flowcytometry and Digital Imaging with Standardized Manual Microscopic Testing [PDF]

open access: diamond
Nur Fitri Hayati Melida Ritonga   +4 more
openalex   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

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