Results 161 to 170 of about 277,529 (354)

Variance log histogram and multifocus image fusion for autofocusing microscopic image on Tuberculosis screening

open access: green, 2018
Budi Santoso   +3 more
openalex   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

FTIR microscopic image analysis based on 2DPCA [PDF]

open access: yes, 2012
In order to improve the efficiency of spectral unmixing,a novel spectral unmixing method based on 2DPCA in the spectral direction was developed.With the proposed method,spectra can be unmixed directly using the original image matrices.Simulation ...
Ming-liang ZHONG   +3 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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