Results 81 to 90 of about 1,009,075 (346)

Colour model analysis for microscopic image processing

Diagnostic Pathology, 2008
This article presents a comparative study between different colour models (RGB, HSI and CIEL*a*b*) applied to a very large microscopic image analysis.
García-Rojo Marcial, González Jesús, Déniz Oscar, González Roberto, Bueno Gloria   +4 more
doaj   +1 more source

A Microscopic Model for Packet Transport in the Internet

, 2001
A microscopic description of packet transport in the Internet by using a simple cellular automaton model is presented. A generalised exclusion process is introduced which allows to study travel times of the particles ('data packets') along a fixed path ...
Andreas Schadschneider, Csabai, Hinrichsen, Huberman, Krug, Leland, Michael Schreckenberg, Nagel, Ohira, Robert Barlovic, Takayasu, Takayasu, Takayasu, Torsten Huisinga, Vandewalle, Willinger, Wolfgang Knospe, Yuan   +17 more
core   +3 more sources

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

DEM investigation of weathered rocks using a novel bond contact model

Journal of Rock Mechanics and Geotechnical Engineering, 2015
The distinct element method (DEM) incorporated with a novel bond contact model was applied in this paper to shed light on the microscopic physical origin of macroscopic behaviors of weathered rock, and to achieve the changing laws of microscopic ...
Zhenming Shi, Tao Jiang, Mingjing Jiang, Fang Liu, Ning Zhang   +4 more
doaj   +1 more source

Towards a Microscopic Model of Magnetoelectric Interactions in Ni3V2O8

, 2005
We develop a microscopic magnetoelectric coupling in Ni$_3$V$_2$O$_8$ (NVO) which gives rise to the trilinear phenomenological coupling used previously to explain the phase transition in which magnetic and ferroelectric order parameters appear ...
A. Aharony, A. B. Harris, A. B. Harris, A. J. C. Wilson, E. E. Sauerbrei, E. P. Wigner, J. R. D. Copley, M. Tinkham, O. Entin-Wohlman, T. Yildirim   +9 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Homogenized dynamics of stochastic partial differential equations with dynamical boundary conditions

, 2007
A microscopic heterogeneous system under random influence is considered. The randomness enters the system at physical boundary of small scale obstacles as well as at the interior of the physical medium.
A. Bensoussan, A. Cherkaev, A. Mikelić, A.K. Nandakumaran, A.K. Nandakumaran, B. Maslowski, B.L. Rozovskii, C. Timofte, D. Cioranescu, D. Cioranescu, D. Cioranescu, D. Cioranescu, D. Yang, E. Pardoux, G. Allaire, G. Allaire, G. Da Prato, G. Prato Da, G.D. Maso, H. Triebel, H. Watanabe, H.J. Kushner, I. Chueshov, J. Duan, J. Escher, J. Escher, J. Souza, J.L. Lions, J.P. Peixoto, Jinqiao Duan, K. Yosida, L.A. Caffarelli, M. Briane, M. Vanninathan, M.B. Taghite, M.L. Kleptsyna, N. Fusco, P.L. Lions, R. Vold, R.E. Langer, R.M. Dudley, S. Albeverio, S. Brahim-Otsmane, S. Wright, S.N. Antontsev, T. Hintermann, T.E. Duncan, V.A. Marchenko, V.V. Jikov, V.V. Zhikov, V.V. Zhikov, W. Wang, Wei Wang, X. Blanc, Z. Huang   +54 more
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Sensitivity Analysis in Traffic Microscopic Simulation Model for Roundabouts

The Baltic Journal of Road and Bridge Engineering, 2013
In the literature, many analytical techniques allow the study of the performance (capacity, queues, delays, etc) of roundabouts which are divided into two groups: analytical models and microscopic simulation models.
Rosolino Vaiana, Vincenzo Gallelli, Teresa Iuele   +2 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source