Results 71 to 80 of about 14,500,098 (303)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Microscopic Model of Superconductivity in Carbon Nanotubes [PDF]
We propose the model of a manifold of one-dimensional interacting electron systems to account for the superconductivity observed in ropes of nanotubes. We rely on the strong suppression of single-particle hopping between neighboring nanotubes in a disordered rope and conclude that the tunnelling takes place in pairs of electrons, which are formed ...
openaire +3 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Research Progress and Prospect of Fission Yield in China Institute of Atomic Energy
Fission yield is one of the crucial data for nuclear power application and nuclear devices development, and plays an important role in the fundamental research such as nuclear fission physics research, element synthesis in nuclear astrophysics, and the ...
SHU Nengchuan1, LIU Lile1, LIU Chao1, YANG Yi1, WANG Xiufeng2, QIAO Chunyuan3, LI Zeyu1, CHEN Yongjing1, GE Zhigang1, LIU Shilong1, , RUAN Xichao1, , CHEN Dongfeng1
doaj +1 more source
Microscopic model for a Brownian translator
Abstract A microscopic model for a translational Brownian motor, dubbed a Brownian translator, is introduced. It is inspired by the Brownian gyrator described by Filliger and Reimann (2007 Phys. Rev. Lett. 99 230602).
WIJNS, Bart +2 more
openaire +4 more sources
Microscopic Modeling of GaN‐based Heterostructures
Self‐consistent quantum modeling of GaN‐based nanostructure are presented. The tight‐binding approach is used to calculate optical properties while optimized effective mass approaches are used to obtain the output characteristics of GaN HEMT.
F. Sacconi +3 more
openaire +1 more source
Microscopic models of hardness [PDF]
Recent developments in the field of microscopic hardness models have been reviewed. In these models, the theoretical hardness is described as a function of the bond density and bond strength. The bond strength may be characterized by energy gap, reference potential, electron-holding energy or Gibbs free energy, and different expressions of bond ...
Gao, F.M., Gao, L.H.
openaire +2 more sources
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

