Results 81 to 90 of about 14,500,098 (303)
Colour model analysis for microscopic image processing
Diagnostic Pathology, 2008 This article presents a comparative study between different colour models (RGB, HSI and CIEL*a*b*) applied to a very large microscopic image analysis.
García-Rojo Marcial +4 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Microscopic study of 117Te isotope using projected shell model [PDF]
EPJ Web of ConferencesA microscopic analysis of the nuclear structure of the odd-mass 117Te has been carried out using the theoretical framework of the Projected Shell Model (PSM). The tellurium isotopes lie in a transitional region near the closed proton shell at Z=50, where
Kumar Amit +5 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Three-dimensional multi-mechanism bounding surface model for sands
Yantu gongcheng xuebao, 2017 Within the multi-mechanism framework, a novel constitutive model for sands is proposed based on the critical state and bounding surface plasticity theories. The model assumes that the macroscopic deformation behavior of sands can be obtained by summation
FANG Huo-lang 1, 2, SHEN Yang 1, ZHENG Hao 1, ZENG Ze-bin 3
doaj +1 more source
Road traffic can be predicted by machine learning equally effectively as by complex microscopic model. [PDF]
Sci Rep, 2023 Sroczyński A, Czyżewski A.
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A microscopic model of wave-function dephasing and decoherence in the double-slit experiment. [PDF]
Sci Rep, 2021 Ramakrishna S.
europepmc +1 more source