Results 101 to 110 of about 1,011,329 (344)

DATA COLLECTION METHOD FOR PEDESTRIAN MOVEMENT VARIABLES

open access: yesCivil Engineering Dimension, 2000
The need of tools for design and evaluation of pedestrian areas, subways stations, entrance hall, shopping mall, escape routes, stadium etc lead to the necessity of a pedestrian model.
Hajime Inamura   +2 more
doaj  

Microscopic biophysical model of self-organization in tissue due to feedback between cell- and macroscopic-scale forces

open access: yesPhysical Review Research, 2020
We develop a microscopic biophysical model for self-organization and reshaping of artificial tissue, that is codriven by microscopic active forces between cells and an extracellular matrix (ECM), and macroscopic forces that develop within the tissue ...
J. P. Hague   +4 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Homogenized dynamics of stochastic partial differential equations with dynamical boundary conditions

open access: yes, 2007
A microscopic heterogeneous system under random influence is considered. The randomness enters the system at physical boundary of small scale obstacles as well as at the interior of the physical medium.
A. Bensoussan   +54 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Nuclear α-cluster structures from valence-space microscopic cluster model

open access: yesPhysics Letters B
Alpha clustering is an important dynamic in nuclear physics, with growing interest to its study in heavy nuclei in recent years. Theoretically, the microscopic cluster models taking nucleons as relevant degrees of freedom have been widely used to study α-
Zhen Wang, Dong Bai, Zhongzhou Ren
doaj   +1 more source

Local equilibrium in heavy ion collisions. Microscopic model versus statistical model analysis [PDF]

open access: yes, 2005
The assumption of local equilibrium in relativistic heavy ion collisions at energies from 10.7 AGeV (AGS) up to 160 AGeV (SPS) is checked in the microscopic transport model. Dynamical calculations performed for a central cell in the reaction are compared
Bass, Steffen A.   +13 more
core  

Macroscopic-Microscopic Mass Models

open access: yes, 1995
10 pages. LaTeX. Presented at International Conference on Exotic Nuclei and Atomic Masses (ENAM 95), Arles, France, June 19-23, 1995. To be published in conference proceedings by Les Editions Frontieres, Gif sur Yvette, France. Seven figures not included here. PostScript version with figures available at http://t2.lanl.gov/pub/publications/publications.
Nix, J. R., Moller, P.
openaire   +2 more sources

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