Results 101 to 110 of about 432,756 (308)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Towards a real-time microscopic emissions model [PDF]

open access: yes, 2001
This article presents a new approach to microscopic road traffic exhaust emission modelling. The model described uses data from the SCOOT demand-responsive traffic control system implemented in over 170 cities across the world. Estimates of vehicle speed
Bell, Margaret   +5 more
core   +1 more source

Sensitivity Analysis in Traffic Microscopic Simulation Model for Roundabouts

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2013
In the literature, many analytical techniques allow the study of the performance (capacity, queues, delays, etc) of roundabouts which are divided into two groups: analytical models and microscopic simulation models.
Rosolino Vaiana   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Microscopic Traffic Simulation Model Calibration [PDF]

open access: yes, 2013
This thesis main focus is microscopic traffic sumulation. Part of this work is the design and implementation of microsimulation model based on cellular automaton. Implemented model supports calibration with genetic algorithm.
Pokorný, Pavel
core   +2 more sources

Generalized velocity–density model based on microscopic traffic simulation

open access: yesTransport, 2018
In case of the Intelligent Driver Model (IDM) the actual Velocity–Density law V(D) applied by this dynamic system is not defined, only the dynamic behaviour of the vehicles/drivers is determined.
Oussama Derbel   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The microscopic mechanism associated with mechanical behaviour of sandstone – using bonded particle model [PDF]

open access: yes, 2012
[[abstract]]According to the previous researches of sandstone, it was found that the key microscopic parameters influencing unconfined compressive strength (UCS) are porosity and grain area ratio (GAR).
Weng, M.C., Li, H.H.
core  

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