Results 111 to 120 of about 432,756 (308)

Microscopic biophysical model of self-organization in tissue due to feedback between cell- and macroscopic-scale forces

open access: yesPhysical Review Research, 2020
We develop a microscopic biophysical model for self-organization and reshaping of artificial tissue, that is codriven by microscopic active forces between cells and an extracellular matrix (ECM), and macroscopic forces that develop within the tissue ...
J. P. Hague   +4 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

A Novel Movement Model for Pedestrians Suitable for Personal Navigation [PDF]

open access: yes, 2008
In this paper a combination of two movement models, operating at the microscopic level and suitable for pedestrian navigation is developed and tested. The constituents are a Stochastic Behavioral Movement Model to characterize more random motion and ...
Kaiser, Susanna   +3 more
core  

A Continuum-Microscopic Method Based on IRBFs and Control Volume Scheme for Viscoelastic Fluid Flows [PDF]

open access: yes, 2012
A numerical computation of continuum-microscopic model for visco-elastic flows based on the Integrated Radial Basis Function (IRBF) Control Volume and the Stochastic Simulation Techniques (SST) is reported in this paper.
Mai-Duy, N.   +7 more
core   +1 more source

DATA COLLECTION METHOD FOR PEDESTRIAN MOVEMENT VARIABLES

open access: yesCivil Engineering Dimension, 2000
The need of tools for design and evaluation of pedestrian areas, subways stations, entrance hall, shopping mall, escape routes, stadium etc lead to the necessity of a pedestrian model.
Hajime Inamura   +2 more
doaj  

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

A Microscopic-to-macroscopic Crowd Dynamic Model [PDF]

open access: yes, 2006
This paper presents a model for a two-dimensional pedestrian movement flow. The model is derived by extending a one-dimensional vehicle traffic flow model that uses two coupled partial differential equations (PDEs) to govern vehicular motion.
Al-Nasur, S., Kachroo, Pushkin
core   +2 more sources

DEM investigation of weathered rocks using a novel bond contact model

open access: yesJournal of Rock Mechanics and Geotechnical Engineering, 2015
The distinct element method (DEM) incorporated with a novel bond contact model was applied in this paper to shed light on the microscopic physical origin of macroscopic behaviors of weathered rock, and to achieve the changing laws of microscopic ...
Zhenming Shi   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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