Results 121 to 130 of about 14,500,098 (303)
Appearance of Hagedorn limiting temperature in microscopic model calculations
EPJ Web of Conferences, 2016 One of important consequences of Hagedorn statistical bootstrap model is the prediction of limiting temperature Tcrit for hadron systems colloquially known as Hagedorn temperature.
Zabrodin E. +3 more
doaj +1 more source
An Elementary Microscopic Model of Sympatric Speciation
Using as a narrative theme the example of Darwin’s finches, a microscopic agent-based model is introduced to study sympatric speciation as a result of competition for resources in the same ecological niche. Varying competition among individuals and resource distribution, the model exhibits some of the main features of evolutionary branching processes ...
Bagnoli, F, Matteuzzi, T
openaire +4 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Global phenomenological and microscopic optical model potentials for alpha
EPJ Web of Conferences, 2017 The global phenomenological and microscopic optical model potentials for alpha with the incident energy up to 400 MeV are obtained. The global phenomenological optical model potential is extracted by simultaneously fitting the experimental data of total ...
Guo Hairui +5 more
doaj +1 more source
A MICROSCOPIC DAMAGE MODEL CONSIDERING THE CHANGE OF VOID SHAPE AND APPLICATION IN THE VOID CLOSING
, 1992 A microscopic damage model of ellipsoidal body containing ellipsoidal void for nonlinear matrix materials is developed under a particular coordinate. The change of void shape is considered in this model.
朱明, 金泉林
core +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
, 2021 Bimonthly magazine discussing topics related to aviation and model airplane engines including collecting, restoring, maintaining, and identifying engines, along with ...
The Model Museum, Daniels, Timothy J.
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source