Results 61 to 70 of about 355,295 (195)
Patients with microscopic polyangiitis may have an immune disorder and generate antibodies which may cross-react with foreign proteins. In this article, we report a 71-year-old female case of microscopic polyangiitis patient with positive Hantaan virus ...
Diao ZONGLI +3 more
doaj
Mucosal‐Associated Invariant T Cells in Health and Disease
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source
We present a case of a male patient with chronic renal insufficiency, due to crescentic glomerulonephritis with IgA deposits, who successively developed (idiopathic) thrombocytopenic purpura (ITP) and MPO-ANCA microscopic polyangiitis (MPA) with ...
Alwin Tilanus +3 more
doaj +1 more source
Clinical Images: Angiolymphoid hyperplasia with eosinophilia mimicking Temporal Arteritis
Arthritis &Rheumatology, EarlyView.
Jonas Menz +4 more
wiley +1 more source
A 74‐year‐old woman was treated for 7 years as culture‐negative bronchiectasis before palpable purpura, haemoptysis, and acute kidney injury revealed MPO‐ANCA vasculitis with pauci‐immune crescentic glomerulonephritis. Rituximab‐based induction produced near‐complete resolution of the pulmonary consolidations and sustained clinical remission at 15 ...
Andrew Kim +5 more
wiley +1 more source
Cochlear Implantation in Autoimmune Inner‐Ear Disease: Outcome and Patient‐Reported Benefit
This study demonstrates that patients with secondary autoimmune inner‐ear disease (AIED) achieve significant improvements in speech perception and quality of life following cochlear implantation. Although AIED patients may show slightly lower performance in noisy environments compared to controls, their subjective hearing benefit converges with matched
Merete Hartmann +4 more
wiley +1 more source
ANCA-associated vasculitis in childhood: recent advances
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides are rare systemic diseases that usually occur in adulthood. They comprise granulomatosis with polyangiitis (GPA, Wegener’s), microscopic polyangiitis (MPA) and eosinophilic ...
Marta Calatroni +20 more
doaj +1 more source
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama +16 more
wiley +1 more source
Clinical characteristics and ANCA specificity of granulomatosis with polyangiitis and microscopic polyangiitis patients, according to low or normal plasma complement levels (absolute values) performed before treatment (M/F: male/female; IQR ...
Thierry Lobbedez (2579155) +5 more
core +1 more source
This literature review addresses the epidemiology, genetic markers, pathogenesis, clinical features, and diagnostic approaches of granulomatosis with polyangiitis and microscopic polyangiitis – both antineutrophil cytoplasmic antibody-associated ...
T. M. Reshetnyak +3 more
doaj +1 more source

