Results 41 to 50 of about 6,124 (160)

A case of microscopic polyangiitis with diffuse alveolar hemorrhage and rapidly progressive glomerulonephritis

Apollo Medicine, 2021
Vasculitis is a rare but important cause of diffuse alveolar hemorrhage (DAH) and should be considered in the differential diagnosis of patients who develop rapidly progressive dyspnea with nonresolving alveolar opacities on thoracic imaging.
G Vikram Reddy, Harini Seshadri
doaj   +1 more source

IL‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised LDL and Complement Pathways

Allergy, EarlyView.
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama, Jun Miyata, Takao Mochimaru, Ryuta Onozato, Yo Otsu, Hisashi Sasaki, Keeya Sunata, Shinichi Okuzumi, Katsunori Masaki, Hiroki Kabata, Keinosuke Hizuka, Yoshinori Hasegawa, Ryo Konno, Yusuke Kawashima, Makoto Arita, Shigeharu Ueki, Koichi Fukunaga   +16 more
wiley   +1 more source

Fibrosis-4 index at diagnosis is associated with all-cause mortality in patients with microscopic polyangiitis and granulomatosis with polyangiitis

BMC Gastroenterology, 2019
Background The fibrosis-4 index (FIB-4) has been reported to be associated with all-cause mortality in several chronic diseases. In this study, we investigated whether at diagnosis could be associated with all-cause mortality in patients with microscopic
Hee Jin Park, Jun Yong Park, Seung Min Jung, Jason Jungsik Song, Yong-Beom Park, Sang-Won Lee   +5 more
doaj   +1 more source

Biosimilar Rituximab in ANCA‐Associated Vasculitis Compared to the Originator: A Multicenter Cohort Study

ACR Open Rheumatology, Volume 8, Issue 8, August 2026.
Objective To evaluate the six‐month effectiveness and safety of rituximab biosimilars compared to the originator in granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), and outcomes following originator to biosimilar switching. Methods We recruited adults with GPA or MPA treated with the rituximab originator or a biosimilar for ...
Arielle Mendel, Lillian Barra, Hassan Behlouli, Sasha Bernatsky, Alison H. Clifford, Jan Willem Cohen Tervaert, Natasha Dehghan, Aurore Fifi‐Mah, Jean‐Paul Makhzoum, Rosalie‐Sélène Meunier, Nataliya Milman, Medha Soowamber, Elaine Yacyshyn, Nader Khalidi, Christian Pagnoux   +14 more
wiley   +1 more source

Microscopic Polyangiitis With Positive Hantaan Virus-Specific Immunoglobuline M Antibody Caused by Cross Reaction: A Case Report

The Turkish Journal of Gastroenterology, 2015
Patients with microscopic polyangiitis may have an immune disorder and generate antibodies which may cross-react with foreign proteins. In this article, we report a 71-year-old female case of microscopic polyangiitis patient with positive Hantaan virus ...
Diao ZONGLI, Zhang AIHUA, Wang GANG, Liu WENHU   +3 more
doaj  

A Combined Transcriptomics and Proteomics Approach to Identify Immune Signatures in ANCA‐Associated Glomerulonephritis

ACR Open Rheumatology, Volume 8, Issue 7, July 2026.
Objective Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis often leads to severe kidney damage. To better understand ANCA‐associated glomerulonephritis (AAGN) and identify potential new therapeutic targets, we performed comprehensive transcriptomic and compartmental proteomic analysis of kidney biopsies from 23 patients in the ...
Ivana Stojkic, John P. Shapiro, Arnon Arazi, Huijuan Song, Pearlly Yan, Estela Puchulu‐Campanella, Hubao Wang, William E. Smoyer, Lynn A. Fussner, Anjali Satoskar, Xin Wang, Samir V. Parikh, Stacy P. Ardoin, Dan Koboldt, Brad H. Rovin, Salem Almaani   +15 more
wiley   +1 more source

Pulmonary Limited MPO-ANCA Microscopic Polyangiitis and Idiopathic Lung Fibrosis in a Patient with a Diagnosis of IgA Nephropathy

Case Reports in Nephrology, 2015
We present a case of a male patient with chronic renal insufficiency, due to crescentic glomerulonephritis with IgA deposits, who successively developed (idiopathic) thrombocytopenic purpura (ITP) and MPO-ANCA microscopic polyangiitis (MPA) with ...
Alwin Tilanus, Patricia Van der Niepen, Caroline Geers, Karl Martin Wissing   +3 more
doaj   +1 more source

Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents

Journal of Clinical Periodontology, Volume 53, Issue 7, Page 1100-1198, July 2026.
ABSTRACT Objective To answer the PICoS question ‘in systemically healthy children and adolescents (Population), what are the main features of periodontitis, necrotising periodontal diseases (NPD) and other periodontal conditions (periodontal abscesses, endo‐periodontal lesions, traumatic occlusal forces, prosthesis‐ and tooth‐related factors ...
Inbar Eshkol‐Yogev, Nagore Ambrosio, Cheryl Somani, Elena Figuero, Lior Shapira, Janet Davies   +5 more
wiley   +1 more source

ANCA-associated vasculitis in childhood: recent advances

Italian Journal of Pediatrics, 2017
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides are rare systemic diseases that usually occur in adulthood. They comprise granulomatosis with polyangiitis (GPA, Wegener’s), microscopic polyangiitis (MPA) and eosinophilic ...
Marta Calatroni, Elena Oliva, Davide Gianfreda, Gina Gregorini, Marco Allinovi, Giuseppe A. Ramirez, Enrica P. Bozzolo, Sara Monti, Claudia Bracaglia, Giulia Marucci, Monica Bodria, Renato A. Sinico, Federico Pieruzzi, Gabriella Moroni, Serena Pastore, Giacomo Emmi, Pasquale Esposito, Mariagrazia Catanoso, Giancarlo Barbano, Alice Bonanni, Augusto Vaglio   +20 more
doaj   +1 more source

Performance Characteristics of Anti–Collagen II Antibodies in Relapsing Polychondritis and Related Diseases: Prospective Analysis, Systematic Review, and Meta‐Analysis

Arthritis Care &Research, Volume 78, Issue 6, Page 798-809, June 2026.
Objective Relapsing polychondritis (RP) is a rare disease defined by recurrent cartilaginous inflammation. Anti–collagen II (Col2) antibodies have been proposed as a diagnostic biomarker for RP, but their performance characteristics are not well defined.
Karyssa Stonick, Marcela A. Ferrada, Alice Fike, Kaitlin A. Quinn, Benjamin A. Turturice, Casey Stein, Peter C. Grayson   +6 more
wiley   +1 more source